Port Charles (city)

Port Charles, New York is the fictional setting of the ABC Daytime soap opera  General Hospital, and its now cancelled spin-off Port Charles. Port Charles is also the setting for SOAPnet's primetime GH spin-off, General Hospital: Night Shift. Port Charles can also be retroactively considered as the setting of The Young Marrieds, a short-lived series which ran between 1964 and 1966.

Location
Port Charles is a fictional small to midsized city located in Western New York, most likely on the shores of Lake Ontario between the Buffalo-Niagara Falls and Rochester areas, or possibly north of Buffalo situated on the Niagara River. In 1993, the producers of General Hospital filmed several exterior locations in and around the Western, New York area - including Letchworth State Park, and the village of Perry, New York. Aerial photos of Port Charles occasionally shown on the air are actually shots of the skyline of downtown Rochester.

Within the fictional universe of General Hospital, the city of Port Charles co-exists with the real cities of Buffalo, Niagara Falls and Rochester. Events in the series indicate that Port Charles' is located relatively close to all of these locations, however it is depicted as a city which would constitute a separate metro area. During several episodes aired in 1996, the characters of Laura Spencer and Stefan Cassadine traveled to a house in Rochester to find Laura's long presumed dead mother Lesley Webber. The episodes in which this occurred suggested that Port Charles was a short driving distance from Rochester, though no actual distance was given. However, when Luke and Laura Spencer returned to General Hospital, they made a dramatic entrance at Niagara Falls.

To be separate from but proximate to both Rochester and Buffalo, and located on a body of water (as the "Port" in the name would indicate), Port Charles would likely be located on Lake Ontario north of the city of Batavia.

History
When the series first began, General Hospital was set in an unnamed city or town somewhere in the United States of America. Between 1964 and 1966, Queen's Point, the setting of the short-lived soap opera, The Young Marrieds, was considered to be a suburb of the same (then still unnamed) city that General Hospital was set in (this was part of a plan to feature regular crossovers between the two shows which never materialized due to the cancellation of The Young Marrieds). It wasn't until 1977 that the General Hospital's setting was finally established as being in the fictional city of Port Charles, New York.

Onscreen, Port Charles has had somewhat of an eclectic history. A 1993 storyline saw Lucky Spencer hiding out in catacombs while hiding from Frank Smith. As a result it was revealed that after the city was first settled, an extensive catacomb system was built beneath the city. The catacombs were again referenced in 1997 when Sonny Corinthos and Brenda Barrett were trapped there. The catacombes were run under the Asian Quarter of the city in a 1985 storyline where Frisco Jones, Sean Donely and Suki were hiding from evil mastermind Wu. In 2003, an episode of General Hospital depicted the recollections of an elderly woman (played by Gloria Stewart), whose mobster husband ran a speakeasy during the prohibition era, thus establishing that the mob has long had ties to the city. Racial discrimination has unfortunately played a part in the history of Port Charles. A 1985 storyline revealed that at some point in the city's history, a large ghetto area known as the Asian Quarter was built in order to house the city's Asian population, while a 1994 storyline revealed that one of the city's first African-American council members, Bradley Ward faced opposition from his white counterparts in the 1970s and was later murdered. This storyline also made references to people being refused housing and bank loans on account of race.

Port Charles suffered a hurricane in 1977, but quickly recovered from both that and the Lassa Fever epidemic that followed less than two years later, thus beginning a long tradition of disasters that have plagued the city right up to the modern day. During this time, Mob storylines began being incorporated into the show. In 1979, residents became concerned that Port Charles was being taken over by organized crime. Mob leader Frank Smith was arrested in 1980, thanks to the efforts of Luke and Laura Spencer.

In 1981, Luke and Laura saved the city from being frozen over by Mikkos Cassadine's weather machine. Luke and Laura were hailed as heroes and their wedding was the social event of the year. Robert Scorpio was quickly appointed as police commissioner. Luke ran and won for mayor, but resigned less than two months later after growing tired of the office.

In 1985, Robert Scorpio, along with Frisco Jones, Felicia Scorpio-Jones, and Sean Donely helped bust an extortion ring that was operating within the city's Asian Quarter. Soon afterwards, Robert left town, and his ex-wife Anna Devane was appointed as the new police commissioner in his place. In a storyline twist, the seemingly honest Police chief Bert Ramsey was apparently so embittered at being passed over for promotion in favor of Anna that he became a dirty cop and began operating a money laundering scam known as Operation Tumble Dry. Thanks to the efforts of Anna and a newly returned Robert, the money laundering scam was busted.

Soon, another crime family, the Jeromes, began to infiltrate the city of Port Charles but by the early 1990s, the influence of the Jeromes had somewhat faded due to the efforts of Robert and Anna. In 1992, Anna and Robert were presumed dead in an explosion. Luke and Laura returned to town, and the Smith Mob began to regroup and once again terrorized the citizens of Port Charles. However, Frank Smith was killed and a much more benevolent crime boss in the form of Sonny Corinthos took over organized crime in the city.

Environmental issues also became a concern as some of the residents of Port Charles formed the Greenbelts organization and protested against the arrival of the S.S Tracy, a ship carrying toxic materials that later sank in the Port Charles Harbor, nearly causing an environmental catastrophe. In 1994, Justus Ward and Laura Spencer led protests against a planned incinerator that was to be located in close proximity to the cities' predominantly ethnic neighborhoods. They were successful in stopping the project despite threats to Laura's life and that of her family.

In 1996, the Cassadine family returned to Port Charles as the main nemesis of the Spencers for a second time. Soon, Port Charles was on the brink of financial disaster when the city's biggest employer, the local hospital, went bankrupt. The hospital (and indirectly the town) was saved from considerable financial ruin at the last minute by a considerable financial investment from Stefan Cassadine, son of Mikkos. Luke claimed that Stefan only wished to continue the nefarious deeds carried out by his father and had in fact been behind the hospital's bankruptcy so he could perform a swift takeover in order to establish himself as a pillar of the community, though not many people believed Luke at the time. Stefan died in disgrace years later.

In the mid-1990's and as of now, crime has been growing in Port Charles since Sonny Corinthos took over. This includes a serial killer, who had 15 victims, killing 4 out of the 15, including a Quartermaine and a Jones-Scorpio. In late 2008, the Russian mob invaded Port Charles, setting fire to free clinic, attacking Maxie Jones, kidnapping Jake Spencer, and other things. In late 2010, superstar Brenda Barrett returned to Port Charles bringing many violetice to Port Charles.

In the 21st century, Port Charles would be hit by a number of disasters, including the Port Charles Hotel completely gutted by fire, a two-way train wreck, a hospital quarantine after a mutant strain of encephalitis spread through the town, Metro Court Hotel being taken hostage, and Anthony Zacchara terrorizing residents at Nikolas Cassadine's Black and White Ball, a Hopsital fire closing GH for four months, and a deadly carnival.

Cassadine Industries
This weatlhy, international conglomerate was founded by the Cassadines in the late 70's as a front to cover for their dirty dealings. But the business took off, being controlled by Mikkos Cassadine, Stavros Cassadine, Helena Cassadine, and Nikolas Cassadine among others. Nikolas is currently in charge of the business. It is planned that when he becomes of age, Spencer Cassadine will take over. In December 2005, a single Cassadine Industries account was estimated to be worth $15 million at the time. As of May 2009, Cassadine Industries was estimated to be worth over $20 billion dollars.

The Courthouse
The Port Charles City/County Courthouse is located in the heart of downtown, apparently very close to the PCPD. It consists of courtrooms and offices, which house officials such as Alexis Davis and Scott Baldwin, the District Attorney and Special Prosecutor. In 1998, Carly Corinthos Jacks shot Tony Jones in open court. Faith Rosco was shot and killed here by a sniper in 2005. Jason Morgan and Amelia Joffe came under fire outside of the building in 2007. In 2012, Todd Manning pulled a gun on Sonny Corinthos, only to be stoped by John McBain. It has been the sight of many life changing court battles, including in 2012 when Maxie Jones was sentected to 20 years.

The Docks/Waterfront/Pier
As its name suggests, Port Charles is a major port. The Waterfront district has been under the control of Sonny Corinthos for over a decade, though rival gangs have tried to move in on his territory, such as Lorenzo Alcazar, the Ruiz brothers, and others. Kelly's Diner, a local eatery, is located in this area and the Elm Street Pier is also located here. Majority of the Port Charles waterfront is owned by the Pride-Philips Company, which was given to Courtney Matthews as a thank you from a woman whose life she saved. Courtney later sold Pride-Philips to Lorenzo Alcazar. In 2008, Alexis Davis and Sam McCall are attacked here by the Text Message Killer. On March 17, 2008, one of the warehouses on the docks, an abandoned cannery, exploded. Sonny met with Claudia Zacchara to return Johnny to her. She arrived, and got on the phone with an ally to try and peace with them and Sonny. Meanwhile, Trevor Lansing and sniper stood on a loft in the warehouse, poised to shoot Claudia. Ric Lansing and Marianna Erosa were in another part of it, trying to cover the dead body of Randy. Carly finally finds Michael, where he confesses to shooting Kate. They began to leave and go home. Meanwhile, a bomb is slowly ticking away. Right as the sniper pulls his trigger, the bomb goes of, and an explosion rips through the building. Everyone survives the event, but Carly miscarries her baby. The docks are currently the site of a fake precription drug ring headed up by Jerry Jacks. The ring produces placebos that have claimed at least one life; a female heart patient. Matt Hunter was the prime suspect, but the extent of his involvement cleared. Andrei Karpov currently had a cargo ship, Odyssey, docked in the harbor.

When the Russian mob invaded PC many things happened here including:

On October 31, 2008, Andrei stabbed Sonny, and threw him into the harbor with weights on his ankles. But just in time, Carly jumped in and saved Sonny. Weeks later, on November 7, Sonny killed Karpov here. On December 19, Sasha Donev was shot and killed by a sniper here. In early January 2009, Jason blew up Sonny's latest cargo shipment.

In 2011, Shawn Bulter stops a bomb from going off here and Dante Falconeri is shot here.

Elm Street Pier
Elm Street is a poorer district within the city and is located near the Waterfront. It is notable for being the place where one of the city's most famous and flamboyant residents, Luke Spencer, grew up. Luke's sister, Bobbie, owns a restored brownstone here, which became the residence of several Port Charlesians. Alan Quartermaine and Mike Corbin used this district of Port Charles to meet up with prostitutes while fighting addictions. Maxie Jones was almost raped here after buying hydrocodone for Lucky Spencer. Robert Scorpio was beaten up by Lorenzo Alcazar's enforcers for not revealing the location of Skye Quartermaine, who was pregnant with his child at the time.

The B&N department store is located somewhere in this area. This is also where launch for Spoon Island is located. Many high level Port Charles citizens meet on the Elm St. Pier daily.

ELQ Industries
ELQ Industries, or Edward Louis Quartermaine Industries, is a multinational conglomerate headquartered in Port Charles. Owned by the wealthy Quartermaines, it is one of the largest businesses in the region. Since 1978, Edward Quartermaine has been the sole owner. Current shareholders include Edward Quartermaine, Monica Quartermaine, Tracy Quartermaine, Jasper Jacks, and Carly Jacks, who owns 30%. It is a rival company with nearby Chandler Enterprises and Buchanan Enterprises.

CEOs of ELQ

 * Bold typeface represents the current CEO


 * Edward Quartermaine (1978-1989)
 * Alan Quartermaine (1989-1990)
 * Ned Ashton (1990-1991)
 * Paul Hornsby (1991)
 * Ned Ashton (1991-1996)
 * Edward Quartermaine (1996)
 * Ned Ashton (1996-1999)
 * A.J. Quartermaine (1999-2000)
 * Edward Quartermaine (2000-2001)
 * Skye Chandler-Quartermaine (2001-2002)
 * Co-CEO Edward Quartermaine (2002)
 * Co-CEO Skye Chandler-Quartermaine (2002)
 * Edward Quartermaine (2002)
 * Ned Ashton (2002-2003)
 * A.J. Quartermaine (2003)
 * Ned Ashton (2003-2004)
 * Edward Quartermaine (2004)
 * Tracy Quartermaine (2004-2005)
 * Lorenzo Alcazar (2005)
 * Tracy Quartermaine (2005-present)

Other personnel

 * Those that appear in bold are current personnel


 * Lorenzo Alcazar - Former Stockholder (30%); sold to Carly; former CEO
 * Ned Ashton - Former CEO; Former Stockholder
 * Lee Baldwin - Former Chief Legal Counsel
 * Scott Baldwin - Former stockholder, former Chief Legal Counsel
 * Julia Barrett - Former stockholder
 * Amanda Barrington - Former board member
 * Katherine Bell - Former Stockholder
 * Asher Caldwell - Current employee
 * Skye Chandler-Quartermaine - Former CEO, former Board member
 * Lucy Coe - Former stockholder
 * Michael Corinthos - Former Junior Executive
 * Sonny Corinthos - Board member, Stockholder
 * Alexis Davis - Former Chief Legal Counsel
 * Bill Eckert - Former stockholder
 * Abby Haver - Former Executive Assistant
 * Paul Hornsby - Former CEO
 * Carly Jacks - Stockholder (30%)
 * Jasper "Jax" Jacks - Stockholder
 * Jason Morgan - Stockholder
 * Sam Morgan - Former Employee
 * A.J. Quartermaine - Former CEO, former employee
 * Alan Quartermaine - Former Stockholder; former CEO
 * Alex Quartermaine - Former employee
 * Dillon Quartermaine - Former Employee
 * Edward Quartermaine - Founder, Controlling shareholder, Owner, Chairman of the Board, former CEO
 * Lila Quartermaine - Former Stockholder
 * Monica Quartermaine - Stockholder
 * Tracy Quartermaine - CEO; Board member; stockholder
 * Laura Spencer - Former secretary
 * Luke Spencer - Former employee
 * Cheryl Stansbury - Former employee
 * Justus Ward - Former Board member; former Chief Legal Counsel

Emily Bowen Quartermaine Clinic
After Emily Quartermaine's death, fiancee Nikolas Cassadine carried on Emily's passion for helping the needy by opening a free clinic in her name. He had it established in it in the warehouse district in a formerly condemned building. Early on, it encountered issues when Mayor Floyd tried to have it shut down. Then came Matt Hunter. With him he brought a counterfeit drug scandal. He bought fake meds from Logan Hayes' employer, switched them with the real ones, and re-sold the true drugs. Nadine is now trying to get him to confess. On September 15 2008, Jerry Jacks set fire to the place in order to cover the illegal drugs. Matt, Nikolas, and Nadine were all trapped, but escaped safely. Employees include owner Nikolas Cassadine, Nadine Crowell, Leyla Mir, and Matt Hunter. On September 15, Jerry Jacks detonated a set of explosives in the building, hoping to silence a nosy Nadine. A raging fire ensued, and Nadine and Matt were hospitalized, but Nikolas received only minor injuries. It is currently being rebuilt. It is on Venice Street, in the warehouse district.

The Floating Rib/Jake's
The Floating Rib (formerly Jake's) is a popular bar owned and operated by Coleman Ratcliffe. It was originally operated by a lady named Jake (played by Stella Stevens). In 2012, the name of the bar was changed to The Floating Rib when Luke Spencer paid Coleman to do so. It was renamed after the former restaurant in Port Charles that was open in the 1980s.

General Hospital
General Hospital is a major employer in the city and is the primary hospital for most Port Charles residents.

The exterior shots of the hospital are images of an actual building, the Los Angeles County-USC Medical Center, located just miles from the show's Los Angeles studio.

Greystone Manor
This is the large estate of Sonny Corinthos and bodyguards Max Giambetti and Milo Giambetti. Not visible from the road, it is guarded by Sonny's men. It has a large terrace, beautiful gardens, and a stately guest house. The large garage stores a Maserati Quattroporte. In 2005, a mobster shot up the mansion's living room with a machine gun while Carly, Sam, Ric and Sonny met inside. In 2007, Kate Howard built her house right next door to Sonny's home. Angry about Kate flying her helicopter over his home, Sonny had Jason Morgan shoot a wire that was attached to her helicopter. It suspended a statue over Kate's house, and was headed to drop it in her garden. After he shot, the statue fell through all three floors of the house, destroying the roof, floors, and walls. Former residents include Carly Jacks, Emily Quartermaine, Sam McCall, Kristina Corinthos, Morgan Corinthos,and Michael Corinthos. Sonny's private maid and cook is named Marcella. The address is 120 Shoreline Road, and Kate Howard's is 124 Shoreline Road.

Harborview Towers
This is an upper end apartment complex in downtown Port Charles. It has a view of the lake, and can clearly be seen in the Port Charles skyline. It includes Jason Morgan's penthouse with his wife Sam Morgan and was the previous residence of Damian Spinelli, Carly Jacks and mob boss Sonny Corinthos. Damian Spinelli's room is "regrettably pink." He stayed in the room that Brenda Barrett lived in while she and Jason were in a marriage of convenience. It is across the hall from the room that was going to be the nursery for Samantha McCall's baby, Lila, who was stillborn. Reese Marshall (when dating Sonny) took residence in Sonny's old penthouse. When Reese Marshall was living there, Carly Corinthos broke in and vandalized the entire apartment due to a mental breakdown. Samantha McCall was attacked there by Nico, where Carly helped fight him off. In 2007, Ric Lansing bugged Jason's apartment in order to obtain a guilty plea in the murder or Lorenzo Alcazar. In 2006, a would-be assassin shot a bullet through the window of Jason's apartment. He leaves the bullet hole in the glass to remind him of the choices he's made. In a December 2008 episode, it was indicated that the Metro Court was located directly across from the Harborview Towers. The address is 122 Harbor View Drive.

The Haunted Star
This ship was originally owned by the Cassadine family and was given to Luke and Laura Spencer by Helena Cassadine as a wedding gift in 1981. It has been owned by many different people over the years, but is currently owned by Luke and Laura's daughter Lulu Spencer-Falconeri and Johnny Zacchara, who plan to turn it into a nightclub where Starr Manning will sing.

Kelly's Diner
Waterfront diner and boarding house originally owned and operated by Rose Kelly. It is currently co-owned by Luke and Bobbie Spencer and managed by Shawn Butler.

Lookout Point/Vista Point
The Point, as it's often referred to, is a high vantage point that sits steeply in the woods of Port Charles. It's been the spot of many outings and events in the past. This is where Maxie Jones and Damian Spinelli often go to think. In May 2002, an upset and foggy minded Carly Corinthos drove her car off of one the steep cliffs, causing it to plunge into the lake. In early 2003, Carly pushed Courtney Matthews' car off of the same cliff in order to cover up her involvement in Elizabeth Webber's hit-and-run. In August 2007, Logan Hayes took Lulu Spencer on a picnic date here. In winter 2007, Lorenzo Alcazar kidnapped Lulu, and ordered her exchange to take place at The Point. Hangman's Bridge is located in this general area. In February 2008, Diego Alcazar had planned to hang Sam McCall and Elizabeth Webber off the bridge as a final stand in his role as the Text Message Killer. Right as they arrived, Elizabeth attacked Diego, causing the car to swerve off the bridge and hang there, swaying back and forth. All three lived, but Diego was soon after killed. In December 2008, Johnny Zacchara and Lulu went there to look at the stars. This is when Johnny was almost arrested for lude behavior in November. Lookout Point is located on the same road as Shadybrook Sanitarium, and meets Harbor View Road and Old Bluff Road at a three-way intersection.

Manning Enterprises
Manning Enterprises (formerly Lux Corp.) bought out Kate Howard's fashion magazine Crimson in 2009. In June of 2012, Todd Manning bought the company and renamed it. Todd also bought out Pres Floyd's newspaper The Port Charles Press and renamed it The Sun. Manning Enterprises also owns a cable television network, as stated by Todd on June 18, 2012. Manning Enterprises is the sister company of Llanview, Pennsylvania-based, which Todd co-owns with his sister.

Crimson magazine
Crimson is a fashion magazine ran by Kate Howard. Jasper Jacks helped Kate get the magazine off the ground by becoming a major investor. Kate's offices are at the Metro Court Hotel. Kate hired Maxie Jones as her first assistant, and Lulu Spencer as her second assistant. In 2008, Maxie was almost raped here by Logan Hayes, but he saw Lulu watching from Johnny's penthouse (which is formerly the home of Jasper Jacks). Lulu then accidentally killed him, which put her in Shadybrooke Sanitarium. When Kate was shot, Maxie temporarily took over for her as the top dog at the magazine. In December 2008, Kate held a party at the skyline restaurant to commemorate the re-launch of Crimson under Kate's name. During the party, after giving Carly the same dress that Kate had on, Lulu and Maxie were almost fired. But due to Jax having controlling interest, he prevented the event from taking place. In May 2009, it was revealed that new designs from Crimson were being leaked to Couture, Kate's former magazine now being run by Giselle May. After Damian Spinelli investigated closely, Clarice Bennett was fired from Crimson for her betrayal; but on further inspection, the culprit was revealed to be Kate herself. In 2011, Lulu left Crimson, only later to return. In 2012, Maxie left Crimson when she was sentenced to 20 years in jail. Maxie was later released from jail. Kate then left Crimson in 2012 due to a mental illness and being confined to Shadybrooke. In June of 2012, Todd Manning bought out Lux Corp., to whom Kate had sold the magazine in 2009. Todd renamed the company Manning Enterprises and now owns Crimson magazine.

The Sun tabloid
The Sun (formerly The Port Charles Press and The Port Charles Herald) is the local newspaper in Port Charles. In December of 2011, Pres Floyd bought The Herald and renamed it The Press. In May of 2012, Todd Manning bought it, renamed it again, and reformatted it as a tabloid. Todd also owns a tabloid in Llanview, Pennsylvania by the same name, which he renamed from The Intruder when he bought it in 1995. That tabloid had been founded by his father and inherited by Victor's widow, from whom Todd bought it.

Metro Court Hotel
The Metro Court Hotel is a hotel currently co-owned by Carly Jacks and Kate Howard. It is located at 1420 Courts Lane, Port Charles, New York. It was built by Jasper Jacks on the former site of the Port Charles Hotel, which was destroyed in a fire in 2004, and named after his then-fiancee Courtney Matthews. It is home to many companies, including Crimson, a fashion magazine ran by Kate Howard and owned by Todd Manning.

The PCPD
One of the best known organizations in Port Charles is the Port Charles Police Department. It has handled several crimes in the city, but not always well. It has several officers that are informants to the mob, most notably the late Logan Hayes and Cooper Barrett. Current employees include commissioner Anna Devane, officer Delores Padilla, detectives David Harper and Dante Falconeri, and evidence room file clerk Lulu Spencer-Falconier.

Pentonville Penitentiary
This is considered the "state" jail where convicted felons go. The real Pentonville Prison has had few references, the most recent being the summer of 2007. Jason Morgan was on trial for the murder of Lorenzo Alcazar. Former inmates have included Diego Alcazar, for the drugging and rape of women in Port Charles, and Nikolas Cassadine, for the murder of Helena Cassadine, his insane grandmother. She turned up alive, and Nikolas was released. In 2008, Scott Baldwin petitionined the judge to have Johnny Zacchara sent there for Logan Hayes' murder. In 2010, Michael Corinthos went to Pentonville for the murder of Claudia Zacchara and Jason Morgan pled guilty to some rico violations and had himself sent to Pentonville as well to protect Michael.

Port Charles Park
The Port Charles park is a popular hangout spot, though can be dangerous at times. Elizabeth Webber was raped here, while Michael and Morgan Corinthos were kidnapped by Faith Rosco, Jake Spencer was kidnapped by Maureen Harper, and Georgie Jones was strangled by the Text Message Killer. Maxie Jones was attacked and knocked out there in November 2008.

Pozzulo's/The No Name
Owned by mobsters Sonny Corinthos and Jason Morgan. The No Name is an Italian restaurant located on the west end of Port Charles. It was first frequented by members of the mafia in the 1990s. Local Mobster Sonny Corinthos previously took his then-wife Carly Corinthos Jacks there in the early 2000s. After the former owner died in 2009, Sonny Corinthos purchased the building and opened an office there.

Quartermaine Mansion
The home of the wealthy Quartermaine family, it also features living quarters for several members of the extended family, including the maid Alice Gunderson and Virginia Cooke, better known as "Cook," the chef. Monica Quartermaine is the owner of the Quartermaine mansion, which she often reminds her family of when they begin quarreling, which is an often occurrence in the Quartermaine quarters. She has been known to throw them out of her house. Some scenes have taken place in the Quartermaine boathouse, and there is also a garage with luxury vehicles such as a custom vintage Bentley. Sage Alcazar froze to death in the kitchen's freezer in 2004, and Tracy Quartermaine was tied up in the pantry by Alice in 2005. The address is 66 Harbor View Road.

Shadybrook Sanitarium
Shadybrook is a psychiatric facility located in a small country area in Port Charles on the same road as Lookout Point. It has been home to many patients, including Carly Corinthos, Tracy Quartermaine, Laura Spencer, Lulu Spencer, and Kate Howard. Lainey Winters and Ewen Keenan have offices in the building.

Wyndemere Castle/Spoon Island


Cassadine family home. The island was leased to the Cassadines long ago by a Native American group. It is home to a grand old mansion called Wyndemere, where many noteworthy residents have resided, although no one currently lives there. Wyndemere is considered a castle by many, but Nikolas Cassadine is quick to defend that it is a "mansion."

ADZ Warehouses
A chain of warehouses owned by the mafia members in the "Tumble Dry" money laundering scam.

Asian Quarter
The Asian Quarter is a ghetto district located within Port Charles and is home to a large Asian population. The residents of this part of the city once lived in fear of an extortion ring that dominated the area, but thanks to the efforts of then police commissioner Robert Scorpio, the extortion ring was busted.

Bamboo Bar
A small bar owned by Wu in the Asian Quarter. Has a secret soundproof room where Robin Scorpio and The Ancient One were being held by Wu's people during the Asian Quarter - Black Pearls storyline.

Barney's Place
A downtown bar where in 1976, Jeff Webber attempted to commit suicide after finding out his wife, Monica Bard, had been having an affair with his brother, Rick.

The Campus Disco
This popular establishment was run by Luke Spencer from 1979 - 1980. It closed in 1981 as Disco music went out of style. This is also where Luke Spencer raped his future wife Laura Webber Baldwin.

The Cellar
Located at 324 Wharf Street, Port Charles, NY– Carly Corinthos, proprietor. Opened February 14, 2003. Rekindled night club created from the remnants of “The Flynn’s Club”, a speakeasy that originally opened New Years Eve 1926. Flynn’s was owned by Catherine Flynn, the grandmother of Faith Rosco. On New Year's Eve 2002, Carly and Ric Lansing discovered the speakeasy bricked off in the basement of Kelly’s Diner when they were scouting for a location for her club. The original owner, Catherine Flynn, who had been living in an apartment across the street, told Carly and Ric the club’s history when she observed them breaking through the brick wall. Employees have included Courtney Matthews as hostess. In November 2003, Faith Rosco claimed ownership of the club stating that though Kelly’s Diner and The Cellar occupied the same building, they always had split deeds and while Luke and Bobbie Spencer owned Kelly’s, The Cellar was rightfully Faith’s property by way of inheritance from Catherine. In May 2004, Carly regained control of the club when Justus Ward discovered that Faith’s claim on the property was invalid. Just prior to her hospitalization in Shadybrook in 2005, she closed the club until she was well again. After recovering, she opted to keep The Cellar closed permanently, stating that it took too much time and money to run.

In April 2007, Sonny and Jason begin to consider using The Cellar as a place to hide their shipments, as The Cellar was vacant at the time. Sonny and Jason were soon ambushed by Lorenzo Alcazar's hired thugs.

Club 101
Elegant night club opened in 2002 by Carly Corinthos with Jasper “Jax” Jacks. The club was converted from an old abandoned warehouse on the “bad side of town” under Carly’s supervision. Jax forced Carly out of the partnership due to what Carly because he believed she was embezzling funds, though she believed it was because of her relationship with Sonny Corinthos. He then brought Skye Chandler Quartermaine in as a partner. Employees have included Courtney Matthews.

The Croydon Hotel
Low cost hotel that was run in Port Charles during the 80's. Residents include Laura Templeton, and her sister Jakie. It was demolished in the early 90's.

Deception
Deception Cosmetics: Former CEO-Laura Spencer; Partner-Carly Corinthos; Former models-Brenda Barrett and Gia Campbell.

Delafield's
Club owned and operated by classical pianist Katherine Delafield. Katherine regularly performed as well as did Frisco Jones. This same club had belonged to Duke Lavery and was purchased after his death in 1990.

Donley Shipping
Shipping company once owned by Sean Donley. Formerly managed by Felicia Jones. Former employees include Anna Devane.

Duke's Club
Run by Duke Lavery and Felicia Jones, this club was a popular hangout for Port Charles residents in the late 1980s. Frisco Jones and Terri O'Connor regularly performed. After Duke's death, the club was purchased in 1990 by classical pianist Katherine Delafield and reopened under the name Delafield's.

The Equinox Corporation
Equinox, officially named the Equinox Defense Arms Corporation was a military equipment manufacturer that was first introduced in January 2007. Exquinox manufactured the armored suitcase that lead to the Metro Court Hostage crisis in February 2007. In November 2008, Nadine Crowell and Nikolas Cassadine took them on in order to get back her Aunt Raylene's plow patent. In January 2009, an Equinox airborne biotoxin was released into General Hospital, forever garnering the label of failure.

Fisherman Village
Waterfront development constructed by mobsters in the “Tumble Dry” money laundering scam. Dan Rooney, Commissioner of Waterfront Development, tried to oppose the construction due to the shoddy construction plans, but was silenced in an “accident” arranged by Mr. Big (Co-Police Chief Burt Ramsey).

The Floating Rib
This restaurant, located across the street from General Hospital, was another popular establishment in the early 1980s. Closed during the late 1980’s. On February 23, 2006, Holly Sutton (not knowing that the restaurant was long out of business) demanded that Luke Spencer and Robert Scorpio meet her outside the restaurant with two million dollars for each vial of antidote for the mutant encephalitis virus that had gripped the city that month. A popular massage parlor is now located on this site.

Flynn's Club/The Cellar
A speakeasy that opened on New Years Eve 1926 beneath what is now Kelly’s Diner. The club was owned by Catherine Flynn, wife of mobster Marco Flynn. It was only open for a few hours because at 12:01 A.M. on opening night, a close friend and associate was killed in the club in a mob hit. Marco retaliated that night, but was arrested. He spent the rest of his life in prison. Catherine never had the heart to reopen, and had it boarded up. The club was discovered in 2002 when Carly Corinthos was looking for a location to open a club of her own. She refurbished this speakeasy and reopened it as “The Cellar”.

HTI
A research firm that the WSB had contracted with to find a secret antidote to the DVX's lethal germ MOX 36. The research was conducted by Dr. Eric Ingstrom before being abducted by the DVX. Stockholders in this firm included Greta Ingstrom and various Quartermaines.

Jacks Cosmetics
Jacks Cosmetics: Original founder: Jasper Jacks; Former CEO: Lucy Coe; Other Known Employees: Brenda Barrett (Former Model)

L&B Records
Record label founded by Lois Cerullo and Ned Ashton. Co-owned at one time by Brenda Barrett and Sonny Corinthos. In 1996, control was seized from Lois and Brenda in a purchase by Edward Quartermaine. Lois regained control with the help of Jasper Jacks. Investors have included Lorenzo Alcazar. Vocalists have included Juan Santiago, Brook Lynn Ashton, Mary Mae Ward and Sage Alcazar. Employees included Kristina Cassadine as an assistant to Ned, Dillon Quartermaine as video director, and Nikolas Cassadine as public relations representative.

Luke's Club
This blues club, run by Luke Spencer and Lucy Coe was a popular place to hangout and socialize during the late 1990s. Lily Corinthos was blown up in a car bomb outside the premises in 1996.

Luke's Place
Port Charles' first casino opened by Luke Spencer and D. L. Brock in 1983. This is notable because according to the city charter, only one casino was allowed to operate. After closing the casino when he was elected mayor later that year, he retained the casino rights. Port Charles did not have another casino until he converted his recently reacquired Haunted Star into a casino on December 26, 2003.

The Oasis
Strip club owned by Coleman where Courtney Matthews secretly worked under the name “Daisy” to pay for damages caused by her then husband, A.J. Quartermaine. On August 28, 2002, A.J. destroyed the club in an arson fire after he found out about Courtney’s job.

The Outback
Popular club once owned and operated by Mac Scorpio. Opened in 1991, Connor Olivera managed the club and worked as a singer. In 1992, Bill Eckert became co-owner. Felicia Jones later bought half ownership of the club, and the two married in 1998, making the club a family business. Employees have included Holly Scorpio, Miguel Morez and Robin Scorpio.

The Paradise Lounge
Strip club once owned by Sonny Corinthos. Karen Wexler and Tammy Hansen once worked there as strippers. The club was closed by the PCPD in 1993 for working underage strippers. The phone number was 555-1081.

The Port Charles Hotel
Elegant hotel that stood at 1420 Courts Lane. It was purchased by the Quartermaines in 1993, but was burnt to the ground on February 11, 2004. The Metro Court Hotel was built on the cleared site.

The Recovery Room
Bar & Grill located across the street from General Hospital. Managed by the Scanlon family and Mary Scanlon's husband Victor Collins. Previously managed by Mike Corbin. Popular establishment in the late 1990s.

Rive Gauche
Posh, upscale Italian restaurant in downtown Port Charles. Johnny Zacchara wanted to take Lulu Spencer here on New Year's Eve 2008.

Sonny's Coffee Shop
This coffee shop was opened in December 2006 by Sonny Corinthos to serve as a front for his illegal activity. Sonny frequently worked out of an office in the building. Carly Corinthos took over decorating and added a coffee cart. This is where Max Giambetti was demoted to working when he helped Carly. This is where Lorenzo Alcazar had a hit woman hide a gun. Alcazar retrieved the gun, went into Sonny's back office, and held him at gunpoint. Carly walked in and was able to distract Alcazar from shooting Sonny. Sonny took this chance and shot Alcazar in the head. On November 14, 2008, Sasha Donev sent a gang of goons to trash the coffeehouse and torch it. Little did they know, as the coffeehouse burned, Olivia Falconeri was trapped in the back in Sonny's office. Sonny managed to save her, but the building was burnt to the ground.

Tea House
Nice Chinese restaurant run by Jade Soong. Where friends could meet up, but mostly used by those from the Asian Quarter.

The Ward House
Orphanage started by Mary Mae Ward, named for her son Bradley, a community leader who had died 20 years earlier. Pediatrician Simone Hardy was a volunteer at the home and introduced Mary Mae to Laura Spencer. In 1996, Laura Spencer purchased and operated the orphanage after Mary Mae’s death. Destroyed in an arson fire started by mobster Damian Smith who wanted the land to build a toxic waste incinerator.

World Security Bureau
World Security Bureau (WSB) is an Espionage agency and The nemesis of the WSB was the international organization known as the DVX. One of the WSB's most daring and effective agents was Robert Scorpio who traveled incognito as an international financier and well-know bon vivant. During the 1981 season Scorpio tracked down the Ice Princess, a statue/diamond with a secret formula on its base that as Scorpio warned "could cause cataclysmic global problems" if not recovered. On the trail of this huge uncut diamond, WSB agent O'Reilly, an elderly woman, was killed in a shoot out on the docks. Scorpio was helped by Luke and Laura as all three stowed away aboard a yacht to a tropical island that was the base of mad scientist Mikkos Cassadine who wanted exploit the power of the Ice Princess formula to be "Supreme Commander of the World." Mikkos fell to his death in freezing chamber of a machine designed to freeze the world. With the help of Luke, the machine's code (I-C-E-P-R-I-N-C-E-S-S) was cracked, disaster was averted and democracy was restored to the planet. Scorpio became a recurring character on General Hospital.

The Nurses Ball
From 1994 - 2001, the Nurses Ball was the social event of the year in the Port Charles calendar and is most notable for being a charity event dedicated to raising funds for various HIV/AIDS organizations, both on the show and in reality. The Nurses Ball was held in the Port Charles Hotel (which burned down in 2004). Notably from 1997 until the last ball in 2001, the Nurses ball was usually a major crossover where characters from both Port Charles and  General Hospital got a chance to interact with one another. A train/bus collision interrupted the 2001 event. The event has since been discontinued. The onscreen reasons for this have not been explained, but it is known that rising expenses and budget cuts in the real world, along with the revamp that was made to Port Charles in 2001 were the reasons why the producers of both General Hospital and Port Charles decided to end the annual event. But in 2006, Carly Corinthos held a similar event in which she auctioned off men to have dinner with women, and all of the money was donated to the hospital.

General Hospital Pediatric Ward Christmas party
For many years, the Pediatric Ward Christmas party has been the focus of General Hospital episodes that have aired just before Christmas (usually on the December 24 episode of General Hospital, but sometimes on December 23 or December 22 if December 24 falls during a weekend). It is traditional for the current chief of staff to read the Christmas story to the children during the party. The chief is also accompanied by the General Hospital volunteers dressed up as Mr. and Mrs. Claus, as well as elves. The children of various cast members from the show are often featured as extras in the party scenes playing the sick children from the ward.

The Webbers and Hardys
Steve Hardy was the chief of Staff at General Hospital from the mid 1970s until his death in 1996. Perhaps one of Dr Hardy's biggest achievements was finding a cure to the Lassa Fever epidemic of 1979. He was married to Audrey Hardy for many years, and adopted her son Tom Hardy, who would also become a doctor. His other son, Jeff Webber, is a doctor as well. Jeff's eldest children, Steven and Sarah, are also doctors, while his youngest daughter, Elizabeth, is a nurse. Elizabeth has two children, Cameron Spencer, whom she is raising with Lucky Spencer and Aiden Spencer her biological son with Lucky. She also had another son Jake Spencer whom she also raised with Lucky, but Jake was killed in a hit and run car accident. Audrey, Elizabeth, Steven, Cameron, and Aiden Webber all live in Port Charles.

The Quartermaines
One of the most distinguished families in Port Charles is the Quartermaine family, who moved to the area in 1978 and are best known for running E.L.Q. Industries. The Quartermaines have had a long-standing rivalry with Sonny Corinthos that began when Sonny married Carly Roberts, the former wife of A.J. Quartermaine and forced A.J. to give up parental rights to his and Carly's son Michael. Other Notable rivalries include Tracy vs Alan, Tracy vs Monica, and Ned vs AJ. Dr. Alan Quartermaine was the chief of staff at General Hospital, while his wife Monica is a renowned heart surgeon. Rock star Eddie Maine is also a prominent member of this family. Other Quartermaine's include Tracy Quartermaine, Emily Quartermaine, Skye Quartermaine, Justus Ward, Dillon Quartermaine, Brook Lynn Ashton, and Jason Morgan.

The Spencers
The Spencer family is originally from Port Charles, the two main members Luke and Bobbie Spencer both being born there, but the siblings moved to Florida when they were young after the death of their mother Lena. Luke and Bobbie both moved back to Port Charles in the late 1970s. The Spencer are perhaps best known for supercouple Luke and Laura, who have two children, Lucky and Lulu. Luke also has a son, Ethan Lovett, and Laura's son Nikolas Cassadine is often considered part of the family. Bobbie's daughter Carly Jacks is a prominent person in town, as she owns the Metro Court Hotel. Lucky's ex-wife Elizabeth Webber and their children Cam and Aiden currently live in Port Charles, as do Luke, Bobbie, Carly and her children Michael Corinthos and Josslyn Jacks, and Lulu and her husband Dante Falconeri.

The Cassadines
The Cassadine brothers, Mikkos, Tony and Victor first made their presence in Port Charles felt in 1981, when they caused the infamous blizzard through the use of carbonic snow. Mikkos' younger son Stefan eventually took control of the family and in 1996, he and his nephew Nikolas moved to Port Charles permanently, joined by distant Cassadine cousin Alexis Davis who was later revealed to be Mikkos' illegitimate daughter (Natasha Cassadine) with Swedish opera singer Kristin Bergman. For a time, Stefan owned General Hospital. Stefan's older brother Stavros Cassadine who had previously died, had kidnapped Laura Spencer and together they had Nikolas, before she escaped leaving Nikolas with Stefan. In 2001, the family received another addition when Alexis' long lost sister, Kristina Cassadine (originally Kristina Carter), was brought to town to reunite with her sister by Jasper Jacks. Stefan later died in 2003, but Nikolas remains in the city. From time to time, Nikolas' grandmother Helena, the widow of Mikkos shows up to terrorize various residents of the city. Alexis has given birth to three daughters, Samantha McCall, Kristina Davis, and Molly Lansing. Nikolas now has a child, Spencer Cassadine, with the late Courtney Matthews. Samantha McCall had a daughter Lila McCall with Sonny Corinthos but Lila was stillborn on November 8, 2004. Sam also has a son with Jason Morgan named Jason Morgan, Jr.

The Scorpios
Australian ex-pat Robert Scorpio was Police Commissioner of Port Charles for many years (1982-1985, 1987-1992), and solved numerous mysteries and crimes. Robert was presumed dead in 1992, but later returned to town in 2006 to track down Luke Spencer who had brought the encephalitis outbreak to Port Charles. Now trying to mend his relationship with his daughter and his wife, Robin and Anna Devane. Mac Scorpio is Robert's brother, and Mac has two adopted daughters Maxie Jones and Georgie Jones (deceased). The newest member of the Scorpio family is Robin's daughter with Patrick Drake, Emma Scorpio-Drake.

The Corithoses and the mob
Sonny Corinthos arrived in Port Charles in 1993, and owned and operated a strip club before becoming Port Charles' most powerful mobster in the power struggles that followed Frank Smith's death. Sonny has become known for his relative benevolence compared to other mafia gangs, and his donation of several million dollars was instrumental in setting up the Stone Cates Memorial AIDS Wing at General Hospital.

Sonny befriended Jason Morgan and taught him the business. Today, Jason is Sonny's mob enforcer and his right-hand man. In April of 2008, Sonny signed over the entire Corinthos-Morgan Crime family to Jason after his son Michael was shot. Sonny was trying to escape the dangerous life for his son Morgan, daughter Kristina, and then-fiance, Kate Howard. In March 2009, Jason gave the business back to Sonny.

The Zaccharas
Insane mob boss, Anthony Zacchara came to Port Charles in September 2007. He brought his son, Johnny Zacchara and his lawyer, Trevor Lansing. It turned out that Trevor was the real mob boss. When Anthony jumped off the roof of Wyndemere Castle, he was paralyzed from the neck down and his son Johnny became the new mob boss. Johnny has plans to take down a manipulative Trevor. Claudia Zacchara, who is Johnny's mother (revealed in 2012), arrived in Port Charles on January 31. Clauida married Sonny Corinthos, and was murdered by Sonny's son Michael in November 2009. In 2012, Anthony married Tracy Quartermaine, and Johnny murdered Anthony in May 2012. Current Zaccharas in Port Charles include:
 * Johnny Zacchara

Estates

 * Quartermaine Mansion (66 Harbor View Road) - Monica Quartermaine, Edward Quartermaine, Tracy Quartermaine Zacchara, and Alice Gunderson
 * Greystone Manor (120 Shoreline Road) - Sonny Corinthos, Max Giambetti, and Milo Giambetti
 * Jacks Lake House (657 Harbor View Road) - Carly Jacks and Josslyn Jacks
 * Howard Estate (124 Shoreline Road) - Kate Howard

Houses

 * Davis Home (55 Cherry Lane) - Alexis Davis, Sam Morgan, Kristina Corinthos-Davis and Molly Lansing-Davis
 * Scorpio-Drake Home (Queen's Point suburb) - Patrick Drake and Emma Scorpio-Drake
 * Webber Home (458 Lexington Avenue, Queen's Point suburb) - Elizabeth Webber, Cameron Spencer and Aiden Spencer
 * The Brownstone (1224 Elm Street) - Bobbie Spencer
 * Hardy House (453 Maple Avenue) - Audrey Hardy

Apartments/Lofts

 * Winslow Garden Apartments (114 Clover Avenue, Apartment 68) - Starr Manning and Trey Mitchell.
 * Johnny's Penthouse Apt. (344 West Adams) - Johnny Zacchara
 * Harborview Towers (122 Harbor View Drive, PH #2) - Jason Morgan
 * Olivia's Condo (#3) - Olivia Falconeri
 * Falconeri Loft, Apt. #4B - Dante Falconeri and Lulu Spencer-Falconeri
 * Michael's Apt. (827 Emerson, Apartment 3-C) - Michael Corinthos
 * Steve's Apt. - Heather Webber, Steve Webber

Other Residences

 * Metro Court Hotel (1420 Courts Lane), Room 815 - Anna Devane and Luke Spencer
 * Metro Court Hotel - Todd Manning
 * The Island (The Bahamas) - The frequent vacation home of Sonny Corinthos.
 * Kelly's Diner (324 Wharf Street) - T.J. Ashford and Shawn Butler
 * Pentonville Penitentiary - Matt Hunter

Estates

 * Quartermaine Mansion (66 Harbor View Road) - Former residence of Brook Lynn Ashton, Ned Ashton, Brenda Barrett, Katherine Bell, Emily Bowen-Quartermaine, Lois Cerullo, Skye Chandler-Quartermaine, Michael Corinthos, Carly Jacks, Georgie Jones, Ethan Lovett, Chloe Morgan, Jason Morgan, A.J. Quartermaine, Alan Quartermaine, Dillon Quartermaine, Lila Quartermaine, Luke Spencer, Lulu Spencer, Justus Ward, Maya Ward, Karen Wexler, Dawn Winthrop, and Anthony Zacchara.
 * Greystone Manor (120 Shoreline Road) - Former residence of Brenda Barrett, Morgan Benson, Emily Bowen-Quartermaine, Michael Corinthos, Carly Jacks, Leticia Juarez, Reese Marshall, Jason Morgan, Sam Morgan, Alec Scott, and Claudia Zacchara Corinthos.
 * Alcazar Estate (243 Sky Cliff Road) - Former residence of Lila Rae Alcazar, Lorenzo Alcazar, Skye Chandler-Quartermaine, Michael Corinthos, and Carly Jacks.
 * Zacchara Mansion (257 Cardinal Drive) - Former residence of Trevor Lansing, Anthony Zacchara, Johnny Zacchara, and Claudia Zacchara Corinthos.
 * Wyndemere Castle (Spoon Island)- Former residence of Brook Lynn Ashton, Ned Ashton, Katherine Bell, Emily Bowen-Quartermaine, Gia Campbell, Helena Cassadine, Irina Cassadine, Nikolas Cassadine, Spencer Cassadine, Stefan Cassadine, Cesar Faison, Lucas Jones, Lydia Karenin, Ewen Keenan, Colleen McHenry, Rebecca Shaw, Aiden Spencer, Bobbie Spencer, Cameron Spencer, Jake Spencer, and Elizabeth Webber.
 * Jacks Lake House (657 Harbor View Road) - Former residence of Morgan Benson, Shawn Butler, Michael Corinthos, and Jasper Jacks.

Houses

 * 13 King Street - Former residence of Lesley Webber
 * Spencer Home (formerly the Ward Home) (24 Royal Street) - Former residence of Sly Eckert, Cameron Spencer, Laura Spencer, Lucky Spencer, Luke Spencer, Lulu Spencer, Bradley Ward, Dan Ward, David Ward, Idios Ward, Mary Mae Ward, Elizabeth Webber, and Lesley Webber.
 * Scorpio-Drake Home (Queens Point Suburb) - Former residence of Robin Scorpio-Drake.
 * Davis Home (formerly the Lansing Home) (55 Cherry Lane) - Former Residence of Ric Lansing and Elizabeth Webber.
 * Lavery Home (309 Baptiste Way) - Former residence of Anna Devane and Duke Lavery.
 * Hardy House (453 Maple Avenue) - Former residence of Steve Hardy, Elizabeth Webber, and Sarah Webber.
 * Jacks Home (607 Broadroad Terrace) - Former residence of Morgan Benson, Michael Corinthos, Carly Jacks, and Jasper Jacks.
 * Baldwin Home (777 Douglas Street) - Former residence of Scott Baldwin and Serena Baldwin.
 * Scorpio Home (formerly the Webber Home) (1020 North Yale) - Former residence of Rachel Adair, Brook Lynn Ashton, Matt Hunter, Maxie Hunter, Georgie Jones, Mac Scorpio, Emma Scorpio-Drake, Robin Scorpio-Drake, Felicia Scorpio-Jones, Laura Spencer, Lesley Webber, and Rick Webber.
 * Webber Home (458 Lexington Avenue, Queen's Point) - Former residence of Jake Spencer.

Apartments/Lofts

 * Winslow Garden Apartments (114 Clover Avenue) - Former residence of Lulu Spencer-Falconeri, Damian Spinelli, and Johnny Zacchara.
 * Harborview Towers (122 Harbor View Drive) - Former residence of Brenda Barrett, Morgan Benson, Kristina Cassadine, Stone Cates, Michael Corinthos, Sonny Corinthos, Alexis Davis, Sean Donely, Tiffany Donely, Maxie Hunter, Carly Jacks, Lucas Jones, Reese Marshall, Courtney Matthews, Hope Morgan, Sam Morgan, Damian Spinelli, and Justus Ward.
 * Ashton Loft (321 Harbor View Road) - Former residence of Ned Ashton, Lois Cerullo, and Alexis Davis.
 * Jones Apt. (2790 Bristol Street: Apartment 3E) - Former residence of Tania Jones and Tony Jones.
 * Sam's Loft (#346) - Former residence of Sam Morgan.
 * Lucky's Apt. (27 S. Patton, Apt. 2B) - Former residence of Aiden Spencer, Cameron Spencer, Jake Spencer, Lucky Spencer, and Siobhan Spencer.
 * Abby's/Michael's Apt. (827 Emerson, Apartment 3-C) - Former residence of Abby Haver and Starr Manning
 * Johnny's Penthouse Apt. (344 West Adams) - Former residence of Anthony Zacchara

Other Residences

 * Kelly's Diner (324 Wharf Street) - Former residence of Diego Alcazar, Brenda Barrett, Coop Barrett, Emily Bowen-Quartermaine, Lily Corinthos, Tammy Hansen, Jimmy Lee Holt, Maxie Hunter, Georgie Jones, Ric Lansing, Courtney Matthews, Miguel Morez, Jason Morgan, Sam Morgan, Celia Quartermaine, Dillon Quartermaine, Edward Quartermaine, Lila Quartermaine, Javier Ruiz, Juan Santiago, Felicia Scorpio-Jones, Rebecca Shaw, Lucky Spencer, Luke Spencer, Holly Sutton, Keesha Ward, and Elizabeth Webber.
 * 860 Birch Tree Lane - Former residence of Brenda Barrett, Emily Bowen-Quartermaine, Jason Morgan, and Zander Smith.
 * The Brownstone (1242 Elm Street) -Former residence of Simone Hardy, Tom Hardy, Tommy Hardy, Maxie Hunter, B.J. Jones, Frisco Jones, Georgie Jones, Lucas Jones, Tony Jones, Felicia Scorpio-Jones, Cheryl Stansbury, and Marcus Taggert
 * The Ianai (Maui, Hawaii) - Former residence of Danny McCall, Jason Morgan and Sam Morgan.
 * Pentonville Penitentiary - Former residence of Carter, Michael Corinthos, Maxie Hunter, Jason Morgan, Anthony Zacchara
 * The Croydon Hotel: Suite 1775 - Former residence of Laura Templeton.
 * Lazarus Yachts I and II - Former residence of Sam Morgan.
 * The Haunted Star Yacht: Suite A1 - Former residence of Luke Spencer.
 * The Haunted Star Yacht: Suite C3 - Former residence of Georgie Jones and Dillon Quartermaine.
 * The Haunted Star Yacht - Former residence of Ethan Lovett
 * Rendezvous Motel, Room 204 - John McBain
 * Rendezvous Motel, Room 205 - Sam Morgan

Metro Court Suites

 * Metro Court Hotel (1420 Courts Lane): Suite 421 - Former residence of Jerry Jacks.
 * Metro Court Hotel: Suite 421 - Former residence of Nikolas Cassadine.
 * Metro Court Hotel: Suite 423 - Former residence of Pres Floyd.
 * Metro Court Hotel: Suite 433 - Former residence of Robert Scorpio.
 * Metro Court Hotel: Suite 483 - Former residence of Max Giambetti.
 * Metro Court Hotel: Suite 487 - Former residence of Diane Miller.
 * Metro Court Hotel: Suite 633 - Former residence of Reese Marshall.
 * Metro Court Hotel: Suite 718 - Former residence of Anna Devane.
 * Metro Court Hotel: Suite 819 - Former residence of Courtney Matthews.
 * Metro Court Hotel: Suite 917 - Former residence of Holly Sutton.
 * Metro Court Hotel: Suite 1205 - Former residence of Olivia Falconeri.
 * Metro Court Hotel: Suite 1220 - Former residence of Carly Jacks.
 * Metro Court Hotel: Suite 5529 - Former residence of Patrick Drake.
 * Metro Court Hotel: Suite 6305 - Former residence of Jasper Jacks.
 * Metro Court Hotel: Suite 6305 - Former residence of Johnny Zacchara.
 * Metro Court Hotel: Suite 6306 - Former residence of Anthony Zacchara.

Port Charles Hotel Suites

 * Port Charles Hotel (1420 Courts Lane): Suite 174 - Former residence of Justus Ward.
 * Port Charles Hotel: Suite 213 - Former residence of Damian Smith.
 * Port Charles Hotel: Suite 244 - Former residence of Mike Corbin.
 * Port Charles Hotel: Suite 347 - Former residence of A.J. Quartermaine.
 * Port Charles Hotel: Suite 683 - Former residence of Alexis Davis.
 * Port Charles Hotel: Suite 753 - Former residence of Faith Rosco.
 * Port Charles Hotel: Suite 778 - Former residence of Ned Ashton.
 * Port Charles Hotel: Suite 885 - Former residence of Frisco Jones.
 * Port Charles Hotel: Suite 918 - Former residence of Jasper Jacks.
 * Port Charles Hotel: Suite 987 - Former residence of Luis Alcazar.
 * Port Charles Hotel: Suite 992 - Former residence of Katherine Bell.
 * Port Charles Hotel: Suite 915 - Former residence of Skye Chandler-Quartermaine.

Mayors

 * Quinn Waser (1969-1974)
 * Bruce Jennings (1974-1979)
 * John Everett (1979-1980)
 * Luke Spencer (1983)
 * Lee Baldwin (1983-1985)
 * Ken Morgan (1985-1989)
 * Earl Richmond (1989-1993)
 * Tom McClintock (1997-2001)
 * Riley Dowd (2001-2006)
 * Garrett Floyd (2006-2011)
 * Janice Lomax (2012-present)

Council Members

 * Casslyn Verga (1986-1991)
 * Dover (1992)
 * Jerry Perez (1994-1996)
 * Ron Blake (1994)
 * Justus Ward (1995-1996)
 * Clemens (1995)
 * A.J. Quartermaine (1996-1997)
 * Raymond (2009)
 * Pete Sorelli (?-present)

Port Charles Police Department

 * Those that appear in bold are current personnel

Chiefs of Police and Police Commissioners

 * Police Commissioner Robert Scorpio (1983-1985)
 * Co-Chief of Police Anna Devane (1985-1986)
 * Co-Chief of Police Burt Ramsey (1985-1986)
 * Chief of Police Anna Devane (1986-1987)
 * Chief of Police Guy Lewis (1987-1992)
 * Police Commissioner Robert Scorpio (1988-1992)
 * Police Commissioner Sean Donely (1992-1995)
 * Police Commissioner Mac Scorpio (1996-2012)
 * Police Commissioner Anna Devane (2012-present)

Other personnel

 * Captain Patterson (1963-1974)
 * Captain Wendell (1974-1979)
 * Police Captain Burt Ramsey (1979-1986)
 * Detective Marcus Taggert(1996-2003)
 * Detective Joe Kelly
 * Detective Frisco Jones
 * Detective Andy Garcia
 * Detective Andy Capelli (2001-2004)
 * Detective Lucky Spencer (2003-2011)
 * Officer Byron Murphy (2004-2005)
 * Dr. Steven Webber (physician specializing in forensic medicine, 2004-2005)
 * Detective Jesse Beaudry (2005-2006)
 * Detective Cruz Rodriguez (2005-2008)
 * Intern Sam McCall (2006)
 * Detective David Harper (2007-present)
 * Police Cadet Cooper Barrett (2007-2008)
 * Special Prosecutor Scott Baldwin (2007-2008)
 * Detective Dante Falconeri (2010-present)
 * Lieutenant Detective Ronnie Dimestico (2010-2012)
 * Officer Delores Padilla (2011-present)
 * Dr. Ewen Keenan (psychological profiler, 2012-present)
 * Lulu Spencer-Falconeri (evidence room file clerk, 2012-present)

District Attorney's office

 * Those that appear in bold are current personnel

District Attorneys

 * Chase Murdoch (1966-1971, 1973-1979)
 * Mitch Williams (1979-1980)
 * Bill Richardson (1982-1983)
 * Mick Boyer (1984)
 * Ken Morgan (1984-1985)
 * Brett Madison (1986)
 * D.A. Lombardi (1986)
 * Michael Schultz (1990-1991)
 * Abbey Mitchell (1993)
 * Michael Schultz (1994)
 * Justus Ward (1998)
 * Scott Baldwin (2002-2004)
 * Ric Lansing (2004-2005)
 * John Durant (2005-2006)
 * Alexis Davis (2005-2006)
 * Ric Lansing (2006-2008)
 * Alexis Davis (2008-2009)
 * D.A. Martinez (2012)
 * D.A. Campbell (2012-present)

Assistant District Attorneys

 * Xavier Coons (1967-1973)
 * Ross Jenelle (1974)
 * Mitch Williams (1978)
 * Scott Baldwin (1988)
 * Jessica Holmes (1992)
 * Dara Jensen (1996-2003)
 * Ric Lansing (2004)
 * Alexis Davis (2006)
 * Job Eliminated (2006-2009)
 * Louise Addison (2009-present)

Legal Facilities

 * Port Charles Police Department
 * Pentonville Penitentiary
 * Statesville Prison
 * Port Charles Courthouse
 * Port Charles City Hall
 * Mason, Petrovich, and Miller Law Firm

Transportation

 * Port Charles Airport
 * Star Fall (airline charter)
 * Slick's Taxi Service

Education

 * Those that appear in bold are current students or staff


 * Winston School - Former students include Molly Lansing-Davis and Kristina Corinthos-Davis
 * Madison Prep - Former students include Kristina Corinthos-Davis, Michael Corinthos, and Kiefer Bauer
 * Queen of Angels - Former students include Morgan Benson, Michael Corinthos III
 * Port Charles High School - T.J. Ashford, Molly Lansing-Davis; Former students include Lulu Spencer, Lucky Spencer, Elizabeth Webber, Emily Bowen-Quartermaine, Sarah Webber, Nikolas Cassadine, Maxie Hunter, Georgie Jones, Lucas Jones, Brenda Barrett, Karen Wexler, Jagger Cates, Laura Spencer, Scott Baldwin, Robin Scorpio-Drake, and Sly Eckert.
 * Charles Street High School
 * Port Charles University (PCU) - Shawn Butler (academic counselor), Michael Corinthos, Dr. Pete Marquez (former professor), former students include Lulu Spencer, Maxie Hunter, Georgie Jones (at time of death), Diego Alcazar, Lucas Jones, Dillon Quartermaine, Brook Lynn Ashton, Robin Scorpio, Damian Spinelli, Felicia Jones, Jade Soong, and Laura Spencer.

Religion

 * Those that appear in bold are current personnel


 * St. Timothy's Church - Father Coates (priest), Mateo Ruiz (former priest)
 * Queen of Angels Church
 * Mount Hebron Church - Bradley Ward (former pastor)
 * General Hospital Chapel
 * Sailor's Chapel
 * St. Anne's Cemetery

Medical

 * General Hospital
 * Mercy Hospital
 * County Hospital
 * Emily Bowen-Quartermaine Memorial Clinic
 * Roselawn Sanitarium
 * Shadybrook Sanitarium
 * Ferncliff Asylum
 * Port Charles Women's Clinic

Chiefs of Staff

 * Bold typeface represents the current Chief of Staff


 * Dr. Bryant Nemer (1966-1971)
 * Dr. Anderson Valey (1971-1976)
 * Dr. Steve Hardy (1976-1996)
 * Dr. Alan Quartermaine (1996-1998)
 * Dr. Monica Quartermaine (1998-1999)
 * Dr. Alan Quartermaine (1999-2007)
 * Dr. Russell Ford (2007-2008)
 * Dr. Patrick Drake (2008; interim)
 * Dr. Monica Quartermaine (2008-2009)
 * Dr. Patrick Drake (2009; interim during Monica's tenure)
 * Dr. Steven Webber (2009-2011)
 * Dr. Robin Scorpio-Drake (2011)
 * Dr. Monica Quartermaine (2011-present; interim)

Assistant Chiefs of Staff

 * Dr. Perry Masil (1966-1970)
 * Dr. Wendel Eltoz (1970-1975)
 * Dr. Buzz Stryker (1985-1987)
 * Dr. Monica Quartermaine (1987-1988)
 * Dr. Alan Quartermaine (1988-1990)
 * Dr. Tom Hardy (1990-1991)
 * Position eliminated (1991)

Head Nurses

 * Bold typeface represents the current Head Nurse


 * Lucille Weeks (1963-1976)
 * Audrey Hardy (1976-2006)
 * Epiphany Johnson (2006-present)

Other Personnel

 * Those that appear in bold are current personnel


 * Dr. Rachel Adair (pediatrician, former)
 * Sage Alcazar (candy striper, former)
 * Dr. Andy Archer (anesthesiologist, former)
 * Dr. Gail Baldwin (psychiatrist, former)
 * Dr. Tom Baldwin (cardiologist, former)
 * Dr. Saira Batra (doctor specializing in Holistic health, former)
 * Melissa Bedford (nurse, former)
 * Carly Benson (physical therapist, former)
 * Meg Bentley (nurse, former)
 * Dr. Emily Bowen-Quartermaine (intern, former)
 * Jessie Brewer (nurse, former)
 * Dr. Phil Brewer (cardiologist, former)
 * Dr. Ellen Burgess (former)
 * Florence Campbell (administrator, former)
 * Nikolas Cassadine (CEO)
 * Stefan Cassadine (CEO, former)
 * Dr. Ryan Chamberlain (pediatrician, former)
 * Betsy Chilson (nurse, former)
 * Dr. Yank Se Chung (former)
 * Judy Clampett (nurse, former)
 * Dr. Kevin Collins (psychiatrist, former)
 * Jolene Crowell (student nurse, former)
 * Nadine Crowell (nurse, former)
 * Howie Dawson (administrator, former)
 * Jane Dawson (nurse, former)
 * Dr. Mark Dante (former)
 * Dr. Ian Devlin (former)
 * Dr. Pierce Dorman (surgeon, former)
 * Dr. Noah Drake (neurosurgeon, former)
 * Dr. Patrick Drake (neurosurgeon)
 * Toussaint Dubois (orderly, former)
 * Iris Fairchild (nurse, former)
 * Dr. Irma Foster (head of psychiatry, former)
 * Audrey Hardy (nurse, former)
 * Dr. Simone Hardy (pediatrician, former)
 * Dr. Steve Hardy (internist, former)
 * Dr. Tom Hardy (psychiatrist, former)
 * Dr. James Hobart (former)
 * Dr. Matt Hunter (neurosurgeon, former)
 * Dr. Terrell Jackson (pediatric surgeon, former)
 * Epiphany Johnson (nurse)
 * Georgie Jones (candy striper, former)
 * Maxie Hunter (candy striper, former)
 * Tania Jones (speech therapist, former)
 * Dr. Tony Jones (neurosurgeon, former)
 * Dr. Kyle Julian (intern, former)
 * Dr. Leo Julian (cardiac surgeon)
 * Dr. Ewen Keenan (psychiatrist)
 * Cassius Kibideaux (orderly, former)
 * Dr. Eve Lambert (physician, former)
 * Dr. Kelly Lee (OB/GYN)
 * Dr. Cameron Lewis (psychiatrist, former)
 * Camillia McKay (nurse, former)
 * Augusta McLeod (nurse, former)
 * Leyla Mir (nurse, former)
 * Miguel Morez (orderly, former)
 * Dr. Lisa Niles (orthopedic surgeon, former)
 * Dr. Kevin O'Connor (former)
 * Dr. Patrick O'Connor (former)
 * Dr. Henry Pinkham (former)
 * Sharon Pinkham (nurse, former)
 * Dr. John Prentice (OB/GYN, former)
 * A.J. Quartermaine (orderly, former)
 * Dr. Alan Quartermaine (general practitioner, former)
 * Dr. Monica Quartermaine (cardiac surgeon)
 * Dan Rooney (administrator, former)
 * Dr. Robin Scorpio-Drake (neuropathologist, former)
 * Rebecca Shaw (x-ray technician, former)
 * Dr. Claire Simpson (intern, former)
 * Iris Sneed (administrator, former)
 * Bobbie Spencer (surgical nurse, former)
 * Dr. Buzz Stryker (former)
 * Diana Taylor (nurse, former)
 * Dr. Peter Taylor (psychiatrist, former)
 * Dr. Asher Thomas (former)
 * Regina Thompson (nurse, former)
 * Dr. Ian Thornhart (former)
 * Amy Vining (nurse, former)
 * Keesha Ward (worked in the Social Work Department, former)
 * Dr. Maya Ward (intern, former)
 * Elizabeth Webber (surgical nurse)
 * Dr. Jeff Webber (physician, former)
 * Dr. Lesley Webber (cardiologist, former)
 * Dr. Rick Webber (surgeon, former)
 * Dr. Sarah Webber (intern, former)
 * Dr. Steven Webber (pediatrician, surgeon)
 * Dr. Karen Wexler (physician, former)
 * Dr. Lainey Winters (psychiatrist, former)
 * Dawn Winthrop (student nurse, former)
 * Dr. Maggie Wurth (pediatrician, former)

Media

 * Those that appear in bold are current personnel


 * WLPC television - Tiffany Hill (former reporter and executive), Shep Casey (former reporter)
 * The Sun tabloid (formerly the Port Charles Press newspaper and the Port Charles Herald newspaper) - Todd Manning (owner, publisher, editor-in-chief, journalist), Diane Miller (columnist), Pres Floyd (former owner and editor-in-chief), Marissa Leong (former reporter)
 * Crimson magazine - Todd Manning (owner), Kate Howard (editor-in-chief), Maxie Hunter (junior editor), Lulu Spencer (former assistant)

Deaths

 * Please note that the deaths listed here did not necessarily take place in the city of Port Charles; rather, this list is of deaths that have either occurred on the show General Hospital, or were of characters from the show.

1950s
Please note, these deaths predate the 1963 premier of General Hospital, and have only been talked about on-air.
 * Lena Spencer - Burst appendix (c1955)

1960s
* denotes a child under the age of 18.
 * Nancy Brewer* - Heart ailment (27 July 1966)
 * John Prentice - Accidental prescription overdose (1967)
 * Polly Prentice - Car crash (1968)

1970s
* denotes a child under the age of 18.
 * Peggy Nelson - Shot and killed by Arnold Nelson (24 September 1971)
 * Meg Baldwin - Stroke during an argument with Lee Baldwin (1971)
 * Tracy Taylor* - Untreated pneumonia (1971)
 * Brooke Clinton - Hit her head in a fall after being hit by Burt Douglas (1973)
 * Kristin Bergman - Throat slit by Helena Cassadine (1973; Revealed in 2001)
 * Joanne Dawson* - (1974)
 * Bradley Ward - Shot and killed by Jack Boland (offscreen) (1 July 1974; Revealed in 1994)
 * Phil Brewer - Bludgeoned with a geode by Augusta McLeod (6 December 1974)
 * Cameron Faulkner - Killed in a car accident caused by Lesley Webber while Cameron was kidnapping her (1976)
 * Martha Taylor* - Killed in a car accident during a hurricane (September 1977)
 * Lamont Corbin - (1978)
 * David Hamilton - Hit his head on a fireplace hearth after being pushed by Laura Webber (1978)
 * Theresa Carter - Hit over the head with a camera by Laura Webber (1978; Revealed in 2002)
 * Beatrice Hewitt - Lassa Fever (1979)
 * Peter Taylor - Heart attack and multiple strokes (1979)

1980s
* denotes a child under the age of 18.
 * Diana Taylor - Accidentally shot and killed by Alice Grant (1981)
 * James Duvall - Hit over the head with the Ice Princess diamond by Alexandria Quartermaine (1981)
 * Brighton O'Reilly - Shot and killed by Victor Cassadine (1981)
 * Maximillian Von Stade - Inadvertently frozen to death in Mikkos Cassadine's Ice Chamber (9 September 1981)
 * Noel Von Stade - Inadvertently frozen to death in Mikkos Cassadine's Ice Chamber (9 September 1981)
 * Alexandria Quartermaine - Inadvertently frozen to death in Mikkos Cassadine's Ice Chamber (9 September 1981)
 * Tony Cassadine - Inadvertently frozen to death in Mikkos Cassadine's Ice Chamber (9 September 1981)
 * Mikkos Cassadine - Thrown into Ice Chamber by Luke Spencer (18 September 1981)
 * Susan Moore - Shot and killed by Crane Tolliver (11 February 1983)
 * Crane Tolliver - Shot and killed by Robert Scorpio (1983)
 * Beatrice LeSeur - Overdose of Diazepam (1983)
 * D.L. Brock - accidentally shot and killed by Ginny Blake (1985)
 * Jennifer Talbot - Strangled to death by Kevin O'Connor (1986)
 * Herbert Quartermaine - Poisoned with arsenic by Betsy Quartermaine (1987)
 * Tania Jones - Killed in a hit and run car accident by a teenager named Cory (18 March 1987)
 * Filomena Soltini - Shot and killed by Cesar Faison (1988)

1990s
* denotes a child under the age of 18.
 * Julian Jerome - Killed in a shootout with Duke Lavery (18 March 1990)
 * Duke Lavery - Killed in a shootout with Julian Jerome (19 March 1990)
 * Dawn Winthrop - Bludgeoned to death with lead pipe by Edge Jerome (27 February 1991)
 * Jessie Wright - Died of old age (offscreen; 30 April 1991)
 * Jessica Holmes - Stabbed to death by Ryan Chamberlain (1993)
 * Ray Conway - Died of a broken neck after being thrown against a wall by Alan Quartermaine (1993)
 * Dominique Stanton Baldwin - Inoperable Brain Tumor (4 May 1993)
 * Bill Eckert - Shot and killed by Frank Smith's men (15 November 1993)
 * B.J. Jones* - Taken off life support after a bus crash (18 May 1994)
 * Frank Smith - Shot and killed by Luke Spencer (30 November 1994)
 * Joe Scully - Shot and killed by Sonny Corinthos (1995)
 * Ryan Chamberlain - Fell into the flames of a broken gas pipe (24 March 1995)
 * Paige Bowen - Breast cancer (9 June 1995)
 * Stone Cates - AIDS related complications (29 November 1995)
 * Mary Mae Ward - Heart attack (17 January 1996; offscreen)
 * Damian Smith - Knocked unconscious with a baseball bat by Justus Ward and died in an arson fire Damian caused (1996)
 * Lily Corinthos - Died in a car bombing meant for Sonny Corinthos, planted by Hernando Rivera (31 May 1996)
 * Steve Hardy - Suffered a fatal heart attack (off-screen) (15 July 1996)
 * Pierce Dorman - Stabbed on orders of Hernando Rivera (1997)
 * Jake Marshak- Hanged to death by serial killer Greg Cooper (June 1998)
 * Grace Sullivan - Drowned in lake by serial killer Greg Cooper (1998)
 * Ruby Anderson - Died in her sleep (offscreen; 28 January 1999)
 * Katherine Bell - Pushed to her death from a parapet by Helena Cassadine (8 October 1999)

2000s
* denotes a child under the age of 18.
 * Cesar Faison - Killed in a boat explosion in Port Charles Harbor, body never recovered (2000)
 * Chloe Morgan - Strangled by Stavros Cassadine (4 September 2001)
 * Stavros Cassadine - Fell to his death in a bottomless pit during a fight with Luke Spencer (9 November 2001)
 * Kristina Cassadine - Caught in an explosion in Sonny Corinthos's warehouse that was caused by Luis Alcazar; died in ICU (6 August 2002)
 * Rick Webber - Hit over the head with a candlestick by Scott Baldwin (12 August 2002, Revealed 2007)
 * Luis Alcazar - Pushed off a balcony fourteen stories to his death by Alexis Davis (22 November 2002)
 * Karen Wexler - Fatally hit by car (1 July 2003)
 * Catherine Flynn - Poisoned with cyanide by Faith Rosco (28 February 2003)
 * Benny Abrahms - Heart attack (13 March 2003)
 * Summer Holloway - Pushed off cliff by Darius Jensen and fell to her death (June 2003)
 * Stefan Cassadine - Stabbed; pushed off a cliff by Luke Spencer and fell to his death (10 October 2003)
 * Cameron Lewis - Caught under falling debris in Port Charles Hotel fire (11 February 2004)
 * Brian Beck - Shot and killed by Andy Capelli (February 2004)
 * Andy Capelli - Shot and killed in a struggle with Jason Morgan (February 2004)
 * Zander Smith - Committed suicide by cop; shot to death by the S.W.A.T. team when he pretended to go for a gun in a standoff (24 March 2004)
 * Ross Duncan - Buldgeoned with a lead pipe to death by Heather Webber (April 2004)
 * Lila Quartermaine - Died in her sleep (off-screen) (14 July 2004)
 * Sage Alcazar* - Stabbed by Mary Bishop and froze to death in the Quartermaine freezer (25 August 2004)
 * Trent Parker - Stabbed with a garden harrow to death by Mary Bishop (27 August 2004)
 * Mary Bishop - Poisoned with penicillin to death by Lorenzo Alcazar (3 September 2004)
 * Connor Bishop - Shot to death by Emily Quartermaine in self defense (25 January 2005)
 * Faith Rosco - Shot by a hitman hired by A.J. Quartermaine; later died in General Hospital (9 March 2005)
 * A.J. Quartermaine - Suffocated by Asher Thomas with a pillow (26 April 2005)
 * Evan Tucker - Hit his head on a rock in a fight with Reese Marshall (17 June 2005)
 * Rachel Adair - Lethal Injection of digitalis by Asher Thomas (27 July 2005)
 * Asher Thomas - Shot and killed by Jason Morgan (8 August 2005)
 * Andrew Domman - Shot and killed by Jason Morgan (August 2005)
 * Javier Ruiz - Shot and killed by Jason Morgan (October 2005)
 * Reese Marshall - Died from a punctured lung in a train crash (15 November 2005)
 * Tony Jones - Died from encephalitis after working tireless hours around the infection (10 February 2006)
 * Courtney Matthews - Died from encephalitis when she was weakened by childbirth (21 February 2006)
 * Danny McCall - Encephalitis (22 February 2006)
 * Jesse Beaudry - Taken off life support after being shot by Manny Ruiz (31 March 2006)
 * Miguel Escobar - Shot and killed by Jason Morgan (31 March 2006)
 * John Durant - Shot and killed by Manny Ruiz (5 May 2006)
 * Justus Ward - Shot and killed by Manny Ruiz (19 June 2006)
 * Manny Ruiz - Pushed from the roof of General Hospital by Jason Morgan (4 July 2006)
 * Aleksander Janacek - Shot and killed by Brenda Barrett while he was strangling Dante Falconeri (offscreen 2007; shown in flashbacks 2010-2011)
 * Alan Quartermaine - Suffered multiple heart attacks after being held hostage by Jerry Jacks (26 February 2007)
 * Lorenzo Alcazar - Shot and killed by Jason Morgan (23 May 2007)
 * Leticia Juarez - Strangled to death by Diego Alcazar (4 September 2007)
 * Emily Bowen-Quartermaine - Strangled to death by Diego Alcazar (1 November 2007)
 * Georgie Jones - Strangled to death by Diego Alcazar (17 December 2007)
 * Stan Johnson - Jerry Jacks had him killed (offscreen) (3 January 2008)
 * Coop Barrett - Hanged to death by Diego Alcazar (25 January 2008)
 * Diego Alcazar - Accidentally hanged himself in a struggle with Nikolas Cassadine and Maxie Jones (6 March 2008)
 * Ian Devlin - Shot and killed by Jason Morgan (5 May 2008)
 * Logan Hayes - Stabbed to death by Lulu Spencer in self defense (9 July 2008)
 * Russell Ford - Killed by a car that crashed into the ER (22 July 2008)
 * Andrei Karpov - Shot and killed by Sonny Corinthos (7 November 2008)
 * Sasha Donev - Shot and killed by a sniper (19 December 2008)
 * Earl Bragg - Ingested toxic spheres (28 January 2009)
 * Andy Archer - Infected with an airborne poison while performing surgery (29 January 2009)
 * Leyla Mir - Infected with an airborne poison while performing surgery (3 February 2009)
 * Trevor Lansing - Accidentally fell off the roof of General Hospital (13 February 2009)
 * Brianna Hughes - Bludgeoned by Andrea Floyd (12 June 2009)
 * Andrea Floyd - Accidentally ran down by Edward Quartermaine (9 September 2009)
 * Claudia Zacchara - Hit over the head with an axe handle by Michael Corinthos III while she was trying to kidnap newborn Josslyn Jacks (4 November 2009)
 * Joey Limbo - Shot by Jason Morgan, then throat crushed by Franco (20 November 2009)

2010s
* denotes a child under the age of 18.
 * Kiefer Bauer - Accidentally ran over by Alexis Davis in a hit and run (6 April 2010)
 * Carter - Stabbed and killed in self defense by Jason Morgan (11 June 2010)
 * Warren Bauer - Shot and killed by Mac Scorpio while Warren was trying to shoot Kristina Corinthos-Davis (23 July 2010)
 * Anton Banavik - Shot and killed by Brenda Barrett while he was trying to kill Dante Falconeri (1 November 2010)
 * Jake Spencer* - Taken off life support after sustaining severe irreparable head trauma due to being ran over by Luke Spencer in a hit-and-run car accident (22 March 2011)
 * Theo Hoffman - Throat slit by his wife Suzanne Stanwyck (31 March 2011)
 * Brandon Lowell - Shot in the head by a hitwoman hired by Anthony Zacchara (5 April 2011)
 * Siobhan Spencer - Poisoned by Anthony Zacchara (22 August 2011)
 * Darryl Hayes - Shot and killed by Lucky Spencer while Darryl was attacking Elizabeth Webber (19 September 2011)
 * Joey Bruzetta - Shot and killed by Johnny Zacchara while Joey was attacking Damian Spinelli and Maxie Jones (19 September 2011)
 * Rudy Trujillo - Shot and killed when Johnny Zacchara forced JT to pull the trigger (20 September 2011)
 * JT - Shot and killed by Rudy Trujillo in self defense (20 September 2011)
 * Captain McLeod - Killed by Lisa Niles (October 2011)
 * Lisa Niles - Bludgeoned with a wrench by Matt Hunter (24 October 2011; offscreen)
 * Abby Haver - Hit by a load that fell off a crane (13 December 2011; offscreen)
 * Lauren Briggs - Framed by Anthony Zacchara for Lisa Niles' murder and supposedly committed suicide (15 December 2011; offscreen)
 * Franco - Shot to death by Jason Morgan (13 January 2012)
 * Chuck Dinafrio - Shot to death by Ronnie Dimestico (25 January 2012; offscreen)
 * Irina Cassadine - Shot and killed by a goon on orders of Helena Cassadine (27 February 2012)
 * Cole Thornhart - Car explosion due to falling off a cliff after a crash caused by Johnny Zacchara shooting out Anthony Zacchara's tires (28 February 2012)
 * Hope Manning-Thornhart* - Car explosion due to falling off a cliff after a crash caused by Johnny Zacchara shooting out Anthony Zacchara's tires (28 February 2012)
 * Ronnie Dimestico - Shot and killed by John McBain while Ronnie was holding a pregnant Sam Morgan hostage. (7 May 2012)
 * Maggie Wurth - Poisoned by Heather Webber and died later at General Hospital (11 May 2012)
 * Anthony Zacchara - Shot multiple times by Johnny Zacchara (22 May 2012)
 * Victor Lord III* - Died of respirator failure shortly after birth (4 June 2012)

Rapes

 * Please note that the rapes listed here did not necessarily take place in the city of Port Charles; rather, this list is of rapes that have either occurred on the show General Hospital, or involved characters from the show.

* denotes that it resulted in a pregnancy
 * Jessie Brewer* - by Phil Brewer (1965) (daughter Nancy Brewer died as an infant)
 * Audrey Baldwin* - by Tom Baldwin (1969) (son Stevie Baldwin was born)
 * Diana Taylor* - by Phil Brewer (1971) (daughter Martha Taylor died as a child)
 * Monica Bard - by Greg Adamson (offscreen; prior to 1976)
 * Lesley Faulkner* - by Cameron Faulkner (1976) (baby was miscarried)
 * Laura Webber - by David Hamilton (statutory; 1977)
 * Laura Baldwin - by Luke Spencer (1979)
 * Monica Quartermaine - by Alan Quartermaine (1979)
 * Laura Spencer* - by Stavros Cassadine (whether it was rape is debatable, 1983) (son Nikolas Cassadine was born)
 * Claudia Zacchara* - by Gino Soleito (statutory; offscreen; 1983; revealed 2012) (son Johnny Zacchara was born)
 * Todd Manning - by Peter Manning (offscreen; 1984)
 * Claudia Zacchara - by Trevor Lansing (statutory; offscreen; c1985)
 * Carly Benson - by Dan Roberts (statutory; offscreen; c1988)
 * Connie Falconeri* - by Joe Scully, Jr. (offscreen; 1990) (a baby boy was born)
 * Carla Greco - by Rico Chacone (1990)
 * Karen Wexler - by Ray Conway (offscreen; prior to 1992)
 * Carol Swift - by Todd Manning (offscreen; c1992)
 * - by Todd Manning, et al. (on OLTL; 1993)
 * Elizabeth Webber - by Tom Baker (1998)
 * Victor Lord, Jr.* - by (on OLTL; 2005) (son  was born)
 * Emily Cassadine - by Connor Bishop (2005)
 * Jasper Jacks - by Irina (2007)
 * - by Victor Lord, Jr. (on OLTL; consensual at the time but later considered rape; 2008)
 * Claudia Zacchara-Corinthos - by Ric Lansing (whether it was rape is debatable, 2009)
 * Michael Corinthos - by Carter (offscreen in 2010; shown in flashback 2011)
 * Sam Morgan - by Franco (offscreen; 2011)

Notable trials

 * Eddie Weeks (reckless driving causing injury, 1963; guilty)
 * Jessie Brewer and Tom Baldwin (murder of John Prentice, 1968; not guilty)
 * Audrey March Hardy (murder of Peggy Nelson, 1971; not guilty)
 * Diana Taylor (murder of Phil Brewer, 1975; not guilty)
 * Anna Devane (attempted murder of Olivia St. John, 1988; acquitted)
 * Felicia Jones (attempted murder of Ryan Chamberlain, 1993; found guilty but later acquitted)
 * Edward Quartermaine (murder of Bradley Ward, 1994; not guilty)
 * Laura Spencer (murder of Damian Smith, 1996; not guilty)
 * Monica Quartermaine (sexual harassment of Pierce Dorman, 1997; guilty, later exonerated)
 * Tony Jones (kidnapping of Michael Corinthos III, 1998; acquitted)
 * Stefan Cassadine (murder of Katherine Bell, 1998; not guilty)
 * Tom Yergin (blackmail of Emily Quartermaine, 1998; guilty)
 * Luke Spencer (murder of Stefan Cassadine, 2000; acquitted)
 * Jason Morgan and Brenda Barrett (murder of Luis Alcazar, 2003; not guilty)
 * Alexis Davis (murder of Luis Alcazar, 2003; acquitted/self-defense)
 * Nikolas Cassadine (murder of Helena Cassadine, 2004; not guilty)
 * Sonny Corinthos (murder of A.J. Quartermaine, 2005; not guilty)
 * Sam McCall (murder of Diego Alcazar, 2006; dismissed)
 * Jason Morgan (murder of Lorenzo Alcazar, 2007; acquitted)
 * Monica Quartermaine (reckless driving causing injury, 2008; sent to rehab)
 * Johnny Zacchara (murder of Logan Hayes, 2008; not guilty)
 * Matt Hunter and Patrick Drake (wrongful death of Brianna Hughes, 2009; charges dropped)
 * Sonny Corinthos (murder of Claudia Zacchara, 2010; charges dropped)
 * Sonny Corinthos (shooting of an occupied vehicle and attempted murder of Anthony Zacchara, and murder with special circumstances of multiple murders and gang murder of Cole Thornhart and Hope Manning-Thornhart, 2012; not guilty)

Disasters

 * In September 1977, a hurricane strikes the city, claiming the lives of Martha Taylor and David Hamilton's wife and child.
 * In 1979, further disaster struck the city, when it was hit by an epidemic of Lassa Fever. General Hospital was quarantined for several weeks until a cure was found.
 * In August 1981 the town experienced a blizzard in the midst of summer. The cause of this blizzard was determined to be Mikkos Cassadine's weather machine.
 * In June 1983, General Hospital was taken hostage.
 * In 1987, a DVX hitman holds several GH staff hostage in the Hospital Cafeteria, threatening to unleash the MOX-36 virus. Bobbie Spencer is stabbed with a syringe filled with the virus and ends up paralyzed from the waist down but eventually recovers.
 * In 1988, a bomb explodes in the main exhibition tent of the Port Charles Art Festival.
 * In 1990, a blackout hit the city when Cesar Faison joined together the alien crystals from the planet Lumina.
 * In February 1991, the Quartermaine S.S. Tracy sank in the middle of Port Charles Harbor, unleashing toxic chemicals and causing an environmental disaster.
 * In 1991, the town experienced an earthquake, which destroyed many homes and caused a lot of damage.
 * In May 1994, a school bus for a Port Charles elementary school crashes, leaving B.J. Jones dead.
 * In June 2001, a bus collided head on with a train near the city, interrupting the Nurses Ball, the social event of the year in Port Charles.
 * In February 2004, the Port Charles Hotel burned down. Zander Smith was believed to be dead. The hotel was completely destroyed, but later rebuilt by Australian billionaire, Jasper Jacks, who renamed it the Metro Court after his now deceased wife, Courtney Matthews.
 * In August 2004, many were trapped at the Quartermaine Mansion while a serial killer was on the loose, killing Sage Alcazar and Trent Parker. This person was Mary Bishop, who also tried to stab Emily Quartermaine.
 * In July 2005, another hurricane strikes the city of Port Charles, but fatalities and damage was light compared to the 1977 hurricane.
 * In November 2005, two trains collided in the Glencoe tunnel which is located near the city. Reese Marshall died. Alexis Davis gave born to Molly Lansing-Davis, with the help of
 * In February 2006, a deadly mutant strain of encephalitis had the hospital quarantined for a month and there were several fatalities.With the help of Carly Jacks and Jason Morgan the antidote was found. Sam's brother Danny died, as well as Courtney Matthews and Tony Jones.
 * In August 2006, another blackout swept through Port Charles. As a result, Alexis, Sonny, and Kristina were stuck in the Metro Court restaurant.
 * In February 2007, the Metro Court Hotel's lobby was taken hostage by Jerry Jacks and eventually, destroyed by an explosion. This hostage situation lasted for 12 hours. Alan died of a heart attack and Robin and Max were shot.
 * In October 2007, Nikolas Cassadine decided to throw a Black and White Ball for Emily Quartermaine and in honor of the late Dr. Alan Quartermaine. Soon enough, disaster struck in the form of Anthony Zacchara. Anthony attacked and hurt Lulu, Ric, Nadine, Maxie, Spinelli, Nikolas, Lucky, Sam,Luke, Leyla, Patrick, Robin, Elizabeth, and Jason. But it later turned out that there was actually a second intruder Diego Alcazar who was the Text Message Killer (TMK). Diego strangled Emily to death, attacked Nikolas, and nearly strangled Carly Jacks to death as well.
 * In late 2007 to early 2008 a killer/stalker was in Port Charles as the Text Message Killer. Carly, Sam, Maxie, Jason, Lucky, Max, Alexis, Nikolas, and Nadine were attacked by him and he murdered Cooper, Emily, Georgie, and Letica . The killer was Diego Alcazar.
 * In January 2008, a man named Joe Smith strapped a bomb to himself, threatening to blow up the ER unless his wife Angie was given medical attention for her pregnancy. Jason, Elizabeth, Monica, Edward, Epiphany, and Jake were some of the hostages. The bomb turned out to be fake.
 * In March 2008, an abandoned cannery warehouse located on the main docks was blown up by a series of bombs that were planted by the late Diego Alcazar. Carly's unborn baby died.
 * In January 2009, a man released five spheres of boitoxin into the air at the hospital, resulting in several explosions and fires. The hospital burned down. Among the hurt and piosinied people from that night were Claudia, Kate, Sam, and many doctors and nurses inculding Elizabeth, Monica, Matt and many more. Leyla, Andy, and Trevor were killed.
 * In September 2009, mayhem breaks loose at a carnival benefit for the Michael Corinthos III Pediatric Head Trauma Wing. The Mayor's wife died and Edward, Jake, Kristina, Max, and Dante were all very hurt.
 * In July 2010, GH goes on lockdown. After just hours after being born, Aiden Cassadine is kidnapped. Kristina Davis is attacked by Warren. Soon after, a shootout accurs leaving Mac Scorpio and Ethan Lovett shot, and Warren dead. During all this, Shirley Smith dies from cancer.
 * From late December 2010 to early January 2011, a bus heading to Cedar Mountain for a ski trip crashes, injuring Olivia Falconeri, Matt Hunter, and Morgan Corinthos, and giving Kristina Davis hypothermia. The bus driver dies on site and Kristina's friend Ali dies at the hospital in front of Kristina.
 * In June 2011, General Hospital is put on lock down when Lisa Niles takes Patrick Drake, Robin Scorpio-Drake, Steven Webber, and Maxie Jones hostage. Spinelli and Patrick get shot and Lisa is left in a coma.
 * In October 2011, Lisa Niles wakes up from her coma to terrioze Port Charles. First she puts a nurse in a coma at GH, drugs Johnny, and stabs Anthony. Then she goes on a boat where Matt is throwing a party. There she kills the caption of the boat, drugs the First Mate, drugs Elizabeth and throws her into the water, drugs Patrick and Robin and intends to infect Patrick with HIV to be stopped by Robin, and lastly she fights Robin on the deck. During this Olivia passes out. Lisa if found dead two weeks later.