Port Charles (city)

Port Charles, New York is the fictional setting of the ABC Daytime soap opera  General Hospital, and its now cancelled spin-off Port Charles. Port Charles is also the setting for SOAPnet's primetime GH spin-off, General Hospital: Night Shift. Port Charles can also be retroactively considered as the setting of The Young Marrieds, a short-lived series which ran between 1964 and 1966.

Location
Port Charles is a fictional small to midsized city located in Western New York, most likely on the shores of Lake Ontario between the Buffalo-Niagara Falls and Rochester areas, or possibly north of Buffalo situated on the Niagara River. In 1993, the producers of General Hospital filmed several exterior locations in and around the Western, New York area - including Letchworth State Park, and the village of Perry, New York. Aerial photos of Port Charles occasionally shown on the air are actually shots of the skyline of downtown Rochester.

Within the fictional universe of General Hospital, the city of Port Charles co-exists with the real cities of Buffalo, Niagara Falls and Rochester. Events in the series indicate that Port Charles' is located relatively close to all of these locations, however it is depicted as a city which would constitute a separate metro area. During several episodes aired in 1996, the characters of Laura Spencer and Stefan Cassadine traveled to a house in Rochester to find Laura's long presumed dead mother Lesley Webber. The episodes in which this occurred suggested that Port Charles was a short driving distance from Rochester, though no actual distance was given. However, when Luke and Laura Spencer returned to General Hospital, they made a dramatic entrance at Niagara Falls.

To be separate from but proximate to both Rochester and Buffalo, and located on a body of water (as the "Port" in the name would indicate), Port Charles would likely be located on Lake Ontario north of the city of Batavia.

History
When the series first began, General Hospital was set in an unnamed city or town somewhere in the United States of America. Between 1964 and 1966, Queen's Point, the setting of the short-lived soap opera, The Young Marrieds, was considered to be a suburb of the same (then still unnamed) city that General Hospital was set in (this was part of a plan to feature regular crossovers between the two shows which never materialized due to the cancellation of The Young Marrieds). It wasn't until 1977 that the General Hospital's setting was finally established as being in the fictional city of Port Charles, New York.

Onscreen, Port Charles has had somewhat of an eclectic history. A 1993 storyline saw Lucky Spencer hiding out in catacombs while hiding from Frank Smith. As a result it was revealed that after the city was first settled, an extensive catacomb system was built beneath the city. The catacombs were again referenced in 1997 when Sonny Corinthos and Brenda Barrett were trapped there. The catacombes were run under the Asian Quarter of the city in a 1985 storyline where Frisco Jones, Sean Donely and Suki were hiding from evil mastermind Wu. In 2003, an episode of General Hospital depicted the recollections of an elderly woman (played by Gloria Stewart), whose mobster husband ran a speakeasy during the prohibition era, thus establishing that the mob has long had ties to the city. Racial discrimination has unfortunately played a part in the history of Port Charles. A 1985 storyline revealed that at some point in the city's history, a large ghetto area known as the Asian Quarter was built in order to house the city's Asian population, while a 1994 storyline revealed that one of the city's first African-American council members, Bradley Ward faced opposition from his white counterparts in the 1970s and was later murdered. This storyline also made references to people being refused housing and bank loans on account of race.

Port Charles suffered a hurricane in 1977, but quickly recovered from both that and the Lassa Fever epidemic that followed less than two years later, thus beginning a long tradition of disasters that have plagued the city right up to the modern day. During this time, Mob storylines began being incorporated into the show. In 1979, residents became concerned that Port Charles was being taken over by organized crime. Mob leader Frank Smith was arrested in 1980, thanks to the efforts of Luke and Laura Spencer.

In 1981, Luke and Laura saved the city from being frozen over by Mikkos Cassadine's weather machine. Luke and Laura were hailed as heroes and their wedding was the social event of the year. Robert Scorpio was quickly appointed as police commissioner. Luke ran and won for mayor, but resigned less than two months later after growing tired of the office.

In 1985, Robert Scorpio, along with Frisco Jones, Felicia Scorpio-Jones, and Sean Donely helped bust an extortion ring that was operating within the city's Asian Quarter. Soon afterwards, Robert left town, and his ex-wife Anna Devane was appointed as the new police commissioner in his place. In a storyline twist, the seemingly honest Police chief Bert Ramsey was apparently so embittered at being passed over for promotion in favor of Anna that he became a dirty cop and began operating a money laundering scam known as Operation Tumble Dry. Thanks to the efforts of Anna and a newly returned Robert, the money laundering scam was busted.

Soon, another crime family, the Jeromes, began to infiltrate the city of Port Charles but by the early 1990s, the influence of the Jeromes had somewhat faded due to the efforts of Robert and Anna. In 1992, Anna and Robert were presumed dead in an explosion. Luke and Laura returned to town, and the Smith Mob began to regroup and once again terrorized the citizens of Port Charles. However, Frank Smith was killed and a much more benevolent crime boss in the form of Sonny Corinthos took over organized crime in the city.

Environmental issues also became a concern as some of the residents of Port Charles formed the Greenbelts organization and protested against the arrival of the S.S Tracy, a ship carrying toxic materials that later sank in the Port Charles Harbor, nearly causing an environmental catastrophe. In 1994, Justus Ward and Laura Spencer led protests against a planned incinerator that was to be located in close proximity to the cities' predominantly ethnic neighborhoods. They were successful in stopping the project despite threats to Laura's life and that of her family.

In 1996, the Cassadine family returned to Port Charles as the main nemesis of the Spencers for a second time. Soon, Port Charles was on the brink of financial disaster when the city's biggest employer, the local hospital, went bankrupt. The hospital (and indirectly the town) was saved from considerable financial ruin at the last minute by a considerable financial investment from Stefan Cassadine, son of Mikkos. Luke claimed that Stefan only wished to continue the nefarious deeds carried out by his father and had in fact been behind the hospital's bankruptcy so he could perform a swift takeover in order to establish himself as a pillar of the community, though not many people believed Luke at the time. Stefan died in disgrace years later.

In the 21st century, Port Charles would be hit by a number of disasters, including the Port Charles Hotel completely gutted by fire, another hurricane hitting the city, a two-way train wreck, a hospital quarantine after a mutant strain of encephalitis spread through the town, Metro Court Hotel being taken hostage, and Anthony Zacchara terrorizing residents at Nikolas Cassadine's Black and White Ball.

General Hospital
General Hospital is a major employer in the city.

Sonny Corinthos built the Stone Cates Memorial AIDS Wing in honor of his friend Stone Cates, who died of AIDS.

Carly Corinthos Jacks built the Michael Corinthos III Pediatric Head Trauma Wing in honor of her son Michael Corinthos III, who was put into a coma after being shot in the head.

In February 2006, a mutant strain of encephalitis placed the hospital under a quarantine, resulting in the deaths of Tony Jones and Courtney Matthews, among others.

In January 2009, an airborne toxin was released into the air by way of five poison spheres, resulting in the deaths of Andy Archer, Trevor Lansing, and Leyla Mir. An oxygen leak resulted in several explosions and fires. The renovations were unveiled on April 13.

In September 2009, tragedy again struck at the hospital. A carnival in the hospital parking lot was set up as a charity to the Michael Corinthos Foundation. A poisoned Edward Quartermaine suffered a massive heart attack, causing him to lose control of his car, crashing it into the crowd. Among the fatalities was Andrea Floyd.

The residents of Port Charles frequent the hospital's West Wing. (Characters on Port Charles were patients in the East Wing.)

The exterior shots of the hospital are images of an actual building, the Los Angeles County-USC Medical Center, located just miles from the show's Los Angeles studio.

Cassadine Industries
This weatlhy, international conglomerate was founded by the Cassadines in the late 70's as a front to cover for their dirty dealings. But the business took off, being controlled by Mikkos Cassadine, Stavros Cassadine, Helena Cassadine, and Nikolas Cassadine among others. Nikolas is currently in charge of the business. It is planned that when he becomes of age, Spencer Cassadine will take over. In December 2005, a single Cassadine Industries account was estimated to be worth $15 million at the time. As of May 2009, Cassadine Industries was estimated to be worth over $20 billion dollars.

The Courthouse
The Port Charles City/County Courthouse is located in the heart of downtown, apparently very close to the PCPD. It consists of courtrooms and offices, which house officials such as Alexis Davis and Scott Baldwin, the District Attorney and Special Prosecutor. In 1998, Carly Corinthos Jacks shot Tony Jones in open court. Faith Rosco was shot and killed here by a sniper in 2005. Jason Morgan and Amelia Joffe came under fire outside of the building in 2007, and it has been the sight of many life changing court battles.

Crimson Magazine
Crimson is a fashion magazine ran by Kate Howard, and the biggest investor is Jasper Jacks. Her offices are at the Metro Court Hotel, which happens to be across the street from Jasper Jacks's penthouse. Kate hired Maxie Jones as her first assistant, and Lulu Spencer her second assistant. In 2008, Maxie was almost raped here by Logan Hayes, but he saw Lulu watching from Johnny's penthouse (which is formerly the home of Jasper Jacks). Lulu then accidentally killed him, which has put her in Shadybrooke. As of recent, Jax has threatened to find someone else to run the magazine if Kate doesn't stop trying to ruin Carly. When Kate was shot on September 26, Maxie temporarily took over for her as the top dog at the magazine. In December 2008, Kate held a party at the skyline restaurant to commmorate the re-launch of Crimson under Kate's name. During the party, after giving Carly the same dress that Kate had on, Lulu and Maxie were almost fired. But due to Jax having controlling interest, he prevented the event from taking place. In May 2009, it was revealed that new designs from Crimson were being leaked to Couture, Kate's former magazine now being run by Giselle May. After Damian Spinelli investigated closely, Clairice Bennett was fired from Crimson for her betrayal. But on further inspection, the culprit was to revealed to be Kate herself.

The Docks/Waterfront/Pier
As its name suggests, Port Charles is a major port. The Waterfront district has been under the control of Sonny Corinthos for over a decade, though rival gangs have tried to move in on his territory, such as Lorenzo Alcazar, the Ruiz brothers, and others. Kelly's Diner, a local eatery, is located in this area and the Elm Street Pier is also located here. Majority of the Port Charles waterfront is owned by the Pride-Philips Company, which was given to Courtney Matthews as a thank you from a woman whose life she saved. Courtney later sold Pride-Philips to Lorenzo Alcazar. On March 17, 2008, one of the warehouses on the docks, an abandoned cannery, exploded. Sonny met with Claudia Zacchara to return Johnny to her. She arrived, and got on the phone with an ally to try and peace with them and Sonny. Meanwhile, Trevor Lansing and sniper stood on a loft in the warehouse, poised to shoot Claudia. Ric Lansing and Marianna Erosa were in another part of it, trying to cover the dead body of Randy. Carly finally finds Michael, where he confesses to shooting Kate. They began to leave and go home. Meanwhile, a bomb is slowly ticking away. Right as the sniper pulls his trigger, the bomb goes of, and an explosion rips through the building. Everyone survives the event, but Carly miscarries her baby. The docks are currently the site of a fake precription drug ring headed up by Jerry Jacks. The ring produces placebos that have claimed at least one life; a female heart patient. Matt Hunter was the prime suspect, but the extent of his involvement cleared. Andrei Karpov currently had a cargo ship, Odyssey, docked in the harbor. On October 31, 2008, Andrei stabbed Sonny, and threw him into the harbor with weights on his ankles. But just in time, Carly jumped in and saved Sonny. Weeks later, on November 7, Sonny killed Karpov here. On December 19, Sasha Donev was shot and killed by a sniper here. In early January, Jason blew up Sonny's latest cargo shipment.

Elm Street Pier
Elm Street is a poorer district within the city and is located near the Waterfront. It is notable for being the place where one of the city's most famous and flamboyant residents, Luke Spencer, grew up. Luke's sister, Bobbie, owns a restored brownstone here, which became the residence of several Port Charlesians. Alan Quartermaine and Mike Corbin used this district of Port Charles to meet up with prostitutes while fighting addictions. Maxie Jones was almost raped here after buying hydrocodone for Lucky Spencer. Robert Scorpio was beaten up by Lorenzo Alcazar's enforcers for not revealing the location of Skye Quartermaine, who was pregnant with his child at the time.

The B&N department store is located somewhere in this area. This is also where launch for Spoon Island is located. Many high level Port Charles citizens meet on the Elm St. Pier daily.

ELQ Industries
ELQ Industries, or Edward Louis Quartermaine Industries is a multinational conglomerate headquartered on Port Charles. Owned by the wealthy Quartermaine's, it is the one of the largest businesses in the region. Since 1978, Edward Quartermaine has been the sole owner, but other employees have included Emily Quartermaine, Lorenzo Alcazar, Carly Corinthos, Sam McCall, Tracy Quartermaine, Alan Quartermaine, Monica Quartermaine, Justus Ward, Jasper Jacks, Laura Spencer, and Luke Spencer. Current shareholders include Edward Quartermaine, Monica Quartermaine, Tracy Quartermaine, Jasper Jacks, and Carly Jacks, who sold 30%. It is a rival company with nearby Chandler Enterprises and Buchanan Enterprises.


 * Edward Quartermaine - Founder, Controlling shareholder, Owner, Chairman of the Board, CEO (on-and-off)
 * Jason Morgan - Stockholder
 * Tracy Quartermaine - CEO; Board member; stockholder
 * Jasper "Jax" Jacks - Stockholder
 * Carly Corinthos - Stockholder (30%)
 * Monica Quartermaine - Stockholder
 * Sonny Corinthos - Board member, Stockholder
 * Laura Spencer - Former Employee
 * Sam McCall - Former Employee
 * Dillon Quartermaine - Former Employee
 * Justus Ward - Former Board member; former Chief Legal Counsel
 * Lorenzo Alcazar - Former Stockholder (30%); sold to Carly
 * Alan Quartermaine - Former Stockholder
 * Lila Quartermaine - Former Stockholder
 * Ned Ashton - former CEO; Former Stockholder
 * Skye Chandler Quartermaine - Former CEO, former Board member
 * AJ Quartermaine - Former CEO (on-and-off)
 * Katherine Bell - Former Shareholder
 * Paul Hornsby - Former CEO
 * Michael Corinthos - Junior Executive
 * Abby Haver - Executive Assistant
 * Asher Caldwell - Current employee

Emily Bowen Quartermaine Clinic
After Emily Quartermaine's death, fiancee Nikolas Cassadine carried on Emily's passion for helping the needy by opening a free clinic in her name. He had it established in it in the warehouse district in a formerly condemned building. Early on, it encountered issues when Mayor Floyd tried to have it shut down. Then came Matt Hunter. With him he brought a counterfeit drug scandal. He bought fake meds from Logan Hayes' employer, switched them with the real ones, and re-sold the true drugs. Nadine is now trying to get him to confess. On September 15 2008, Jerry Jacks set fire to the place in order to cover the illegal drugs. Matt, Nikolas, and Nadine were all trapped, but escaped safely. Employees include owner Nikolas Cassadine, Nadine Crowell, Leyla Mir, and Matt Hunter. On September 15, Jerry Jacks detonated a set of explosives in the building, hoping to silence a nosy Nadine. A raging fire ensued, and Nadine and Matt were hospitalized, but Nikolas received only minor injuries. It is currently being rebuilt. It is on Venice Street, in the warehouse district.

Greystone Manor
This is the large estate of Sonny Corinthos and bodyguards Max Giambetti and Milo Giambetti. Not visible from the road, it is guarded by Sonny's men. It has a large terrace, beautiful gardens, and a stately guest house. The large garage stores a Maserati Quattroporte. In 2005, a mobster shot up the mansion's living room with a machine gun while Carly, Sam, Ric and Sonny met inside. In 2007, Kate Howard built her house right next door to Sonny's home. Angry about Kate flying her helicopter over his home, Sonny had Jason Morgan shoot a wire that was attached to her helicopter. It suspended a statue over Kate's house, and was headed to drop it in her garden. After he shot, the statue fell through all three floors of the house, destroying the roof, floors, and walls. Former residents include Carly Jacks, Emily Quartermaine, Sam McCall, Kristina Corinthos, Morgan Corinthos,and Michael Corinthos. Sonny's private maid and cook is named Marcella. The address is 120 Shoreline Road, and Kate Howard's is 124 Shoreline Road.

The Haunted Star
This ship was a wedding gift to Luke and Laura Spencer. Luke sold it in early 1983 but reacquired it in December 2003. Today, Luke's name remains on the deed, and it now serves as a casino. Previous owners include Jasper Jacks, and Samantha McCall. In 2006, Luke hired Diego Alcazar to pretend to rob the Haunted Star, so he could take the money from his wife and co-owner, Tracy Quartermaine. A previous heist occurred, in 2003 (during the Grand Opening), by Lorenzo Alcazar. Luke's previous partners in the casino also include, Faith Rosco and Skye Quartermaine. Dillon Quartermaine briefly lived on the ship. The ship originally belonged to the aristocratic Cassadine family. Luke later took possession after he defeated Mikkos Cassadine and his plot to freeze the world with a weather machine. Sam McCall is a former employee of the Haunted Star, and Ethan Lovett who is Luke's son is a current employee. His most recent investors were the Zacchara family. Luke is currently living in a private suite onboard.

Harborview Towers
This is an upper end apartment complex in downtown Port Charles. It has a view of the lake, and can clearly be seen in the Port Charles skyline. It includes Jason Morgan's penthouse with Samantha McCall and Damian Spinelli, and was the previous residence of Carly Jacks and mob boss Sonny Corinthos. Damian Spinelli's room is "regrettably pink." He stays in the room that Brenda Barrett lived in while she and Jason were in a marriage of convenience. Also it was going to be the room for Samantha McCall's baby, Lila, who was stillborn and Jason leaves it pink. Reese Marshall (when dating Sonny) took residence in Sonny's old penthouse. When Reese Marshall was living there, Carly Corinthos broke in and vandalized the entire apartment due to a mental breakdown. Samantha McCall was attacked there by Nico, where Carly helped fight him off. In 2007, Ric Lansing bugged Jason's apartment in order to obtain a guilty plea in the murder or Lorenzo Alcazar. In 2006, a would-be assassin shot a bullet through the window of Jason's apartment. He leaves the bullet hole in the glass to remind him of the choices he's made. In a December 2008 episode, it was indicated that the Metro Court was located directly across from the Harborview Towers. The address is 122 Harbor View Drive.

Jake's
Jake's is a popular bar owned and operated by Coleman Ratcliffe. Originally operated by a lady named Jake (played by Stella Stevens). Jason Morgan and Carly Corinthos also first met here over a game of pool in 1996. Robin Scorpio, Emily Quartermaine, Elizabeth Webber, Kelly Lee, and Lainey Winters chose Jake's as the destination for their Girls' Night Out, where they each shared their fantasies about co-worker, Patrick Drake. A Boys' Night Out also took place soon after, with Max Giambetti, Ric Lansing, Patrick Drake, Lucky Spencer, and Nikolas Cassadine, where they each shared fantasies about Carly Corinthos. While unconscious after the cannery explosion, Carly hallucinated that she was there playing pool with Jason, the same way that they first met. It is also here where rivals Claudia Zacchara and Olivia Falconeri first met. For the first time on July 10, Jake's began a weekly karaoke night.

Kelly's Diner
Waterfront diner and boarding house originally owned and operated by Rose Kelly, whose late husband Paddy, had been killed by the Mob.

Almost everyone in town has been to Kelly’s at least once over the years. The diner itself has been a popular gathering place of many of Port Charles’ citizens. Many newcomers to the city have found their way to Kelly’s, where they have rented the rooms above. Edward Quartermaine worked here briefly.

Ruby Anderson stepped in as owner when Rose decided to leave town to work with her stepson Joe in 1984, offering homespun advice—and the best damned chowder and chili in New York State. She was a staple of the diner until her death in 1999.

The establishment was left to Luke and Bobbie Spencer, formerly managed by Tammy Hansen. In February 2004, Bobbie asked Mike Corbin to run the diner. Being a family-owned business, Lucky Spencer, Nikolas Cassadine, Emily Quartermaine, and Elizabeth Webber occasionally had private “Kelly’s-closed dinners” which consisted of traditional potluck dinners.

Characters on the now canceled Port Charles also frequented Kelly's from time to time.

Residents have included Holly Sutton, Jimmy Lee Holt, Celia Quartermaine, Felicia Jones, Edward and Lila Quartermaine, Colton Shore, Charlie Prince, Lily Corinthos, Brenda Barrett, Sam McCall, Miguel Morez, Juan Santiago, Courtney Matthews, Emily Quartermaine, Keesha Ward, Ric Lansing, Lucky Spencer, Diego Alcazar, Brian Beck, Heather Webber, Javier Ruiz, Elizabeth Webber, Lucky Spencer, Maxie Jones, Dillon Quartermaine, Georgie Jones, Coop Barrett, Rebecca Shaw, and Tammy Hansen.

On November 13, 2008, Sasha Donev sent a gang of Russian goons to attack Kelly's. They beat and tried to murder Mike, and torched the diner. Bobbie and Luke had the diner rebuilt to look just as the old one did, with the idea of not straying from Kelly's original roots.

Lookout Point/Vista Point
The Point, as it's often referred to, is a high vantage point that sits steeply in the woods of Port Charles. It's been the spot of many outings and events in the past. This is where Maxie Jones and Damian Spinelli often go to think. In May 2002, an upset and foggy minded Carly Corinthos drove her car off of one the steep cliffs, causing it to plunge into the lake. In early 2003, Carly pushed Courtney Matthews' car off of the same cliff in order to cover up her involvement in Elizabeth Webber's hit-and-run. In August 2007, Logan Hayes took Lulu Spencer on a picnic date here. In winter 2007, Lorenzo Alcazar kidnapped Lulu, and ordered her exchange to take place at The Point. Hangman's Bridge is located in this general area. In February 2008, Diego Alcazar had planned to hang Sam McCall and Elizabeth Webber off the bridge as a final stand in his role as the Text Message Killer. Right as they arrived, Elizabeth attacked Diego, causing the car to swerve off the bridge and hang there, swaying back and forth. All three lived, but Diego was soon after killed. In December 2008, Johnny Zacchara and Lulu went there to look at the stars. This is when Johnny was almost arrested for lude behavior in November. Lookout Point is located on the same road as Shadybrook Sanitarium, and meets Harbor View Road and Old Bluff Road at a three-way intersection.

Metro Court Hotel
The Metro Court Hotel was built by billionaire Jasper Jacks on the site where the Port Charles Hotel once occupied until it was destroyed in a February 2004 fire caused by Edward Quartermaine and is now the town's most popular hotel. The Hotel was named after Courtney Matthews, who was engaged to Jax at the time. The Metro Court is home to many businesses and people, including Crimson, Kate Howard's fashion company and magazine with Jasper Jacks.

In 2006, Manny Ruiz attempted to shoot Jason Morgan on the terrace. Manny shot at him, accidentally hitting Samantha McCall.

Its lobby was recently the site of an explosion where it sustained extensive damage during the final minutes of a twelve hour hostage crisis. Employees and residents were held in the lobby by Jerry Jacks, (then known as James Craig) who was after the contents of a briefcase locked in the hotel vault. This siege lasted. Robin Scorpio was shot in her stomach within the first hour. She was operated on by Emily Quartermaine and Carly Jacks. Max Giambetti was shot in the shoulder. Father Mateo Ruiz was shot for killing one of the mercenaries. The crisis culminated when explosives were detonated in the lobby as the police stormed in. In the aftermath, the Hotel continued to be a major set, as the search for survivors continued, and a gun battle as Jason Morgan pursued James Craig through the rubble. It was rebuilt quickly, with more security. Hostages were Robin Drake, Carly Jacks, Emily Quartermaine, Sonny Corinthos, Max Giambetti, Mateo Ruiz, Alan Quartermaine, Sam McCall, Nikolas Cassadine, Elizabeth Webber, Lulu Spencer, who was held at gunpoint, Maxie Jones, who was locked in a vault the whole time, and later on Damian Spinelli when he was caught trying to help Jason rescue the hostages.

In July 2008, Logan Hayes attacked Maxie Jones in Kate Howard's office, pushing her to the floor. As he went to kill her, he caught Lulu Spencer looking through the window of her office from Johnny's balcony across the street. He ran up to the penthouse, and broke down the door with a fire axe. He tried to talk Lulu into getting back together, and when she refused, Logan tried to rape her. She grabbed a butcher knife from the kitchenette and plunged it onto his stomach. Logan died, and Johnny took the fall for her. Claudia and Johnny dumped his body at Nikolas' clinic.

Current and former employees include Carly Jacks, Jasper Jacks, Sam McCall, Max Giambetti, Cooper Barrett, Nikolas Cassadine, Olivia Falconeri, Marty, Diane, Lori, and Eddie.

Residents include Diane Miller, Olivia Falconeri, and Anna Devane. The hotel boasts a spa, solarium, restaurant, ballroom, and penthouse suites. The hotel is exactly 25 stories tall, excluding the basement. It has several sister hotels, including one named the Bella Maison in Montreal (owned by Carly). It also has sister hotels in Paris, other parts of Europe, and in Hawaii. It is a rival hotel to the Cosmopolitan. It is right across the street from the Harborview Towers.

The address (stated when the Port Charles Hotel stood there) is 1420 Courts Lane.

The No Name/Pozzulo's
Owned by mobsters Sonny Corinthos and Jason Morgan. The No Name is an Italian restaurant located on the west end of Port Charles. It was first frequented by members of the mafia in the 1990s. Local Mobster Sonny Corinthos previously took his then-wife Carly Corinthos Jacks there in the early 2000s. After the former owner died in 2009, Sonny Corinthos purchased the building and opened an office there.

Port Charles Park
The Port Charles park is a popular hangout spot, though can be dangerous at times. Elizabeth Webber was raped here, while Michael and Morgan Corinthos were kidnapped by Faith Rosco, Jake Spencer was kidnapped by Maureen Harper, and Georgie Jones was strangled by the Text Message Killer. Maxie Jones was attacked and knocked out there in November 2008.

The PCPD
One of the best known organizations in Port Charles is the Port Charles Police Department. It has handled several crimes in the city, but not always well. It has several officers that are informants to the mob, most notably the late Logan Hayes and Cooper Barrett. Current employees include commissioner Mac Scorpio, and officers Lucky Spencer, Cruz Rodriguez, and Detective Harper. Scott Baldwin has an office here. In July 2008, it was the sight of a hostage situation. Lulu Spencer smuggled in a gun of Edward Quartermaine's to Johnny Zacchara.

Pentonville Penitentiary
This is considered the "state" jail where convicted felons go. The real Pentonville Prison has had few references, the most recent being the summer of 2007. Jason Morgan was on trial for the murder of Lorenzo Alcazar. Former inmates have included Diego Alcazar, for the drugging and rape of women in Port Charles, and Nikolas Cassadine, for the murder of Helena Cassadine, his insane grandmother. She turned up alive, and Nikolas was released. In 2008, Scott Baldwin petitionined the judge to have Johnny Zacchara sent there for Logan Hayes' murder. In 2010, Michael Corinthos went to Pentonville for the murder of Claudia Zacchara and Jason Morgan pled guilty to some rico violations and had himself sent to Pentonville as well to protect Michael.

Quartermaine Mansion
The home of the wealthy Quartermaine family, it also features living quarters for several members of the extended family, including the maid Alice Gunderson and Virginia Cooke, better known as 'Cook', the chef. Monica Quartermaine is the owner of the Quartermaine mansion, which she often reminds her family of when they begin quarreling, which is an often occurrence in the Quartermaine quarters. She has been known to throw them out of her house. Some scenes have taken place in the Quartermaine boathouse, and there is also a garage with luxury vehicles such as a custom vintage Bentley. Sage Alcazar froze to death in the kitchen's freezer in 2004, and Tracy Quartermaine was tied up in the pantry by Alice in 2005. Former and current residents include Edward Quartermaine, Lila Quartermaine, Alan Quartermaine, Monica Quartermaine, Tracy Quartermaine, Dillon Quartermaine, Skye Quartermaine, Jason Morgan, Emily Quartermaine, Ned Ashton, Luke Spencer, Carly Corinthos, Lulu Spencer, A.J. Quartermaine, Dawn Winthrop, Karen Wexler, Alice Gunderson, Georgie Jones, Michael Corinthos III, Brook Lynn Ashton, Justus Ward, Maya Ward, Ethan Lovett, and Lois Cerullo. The address is 66 Harbor View Road.

Shadybrooke Sanitarium
Shadybrooke is a psychiatric facility located in a small country area in Port Charles. It has been home to many patients, including Carly Corinthos, Tracy Quartermaine, Laura Spencer, and Lulu Spencer. Lainey Winters has an office in the building, and it has become the permanent home to Laura Spencer after her 2002 breakdown, followed by a slip into catatonia. In 2005, Carly stood on the building's ledge, threatening to jump after hearing Sonny Corinthos tell Jason Morgan that her life is over. She came down, and eventually recovered from the breakdown. Laura and Lulu's were both caused by haunting murders: Lulu stabbed Logan Hayes, and Laura thought that she killed Rick Webber after hitting him with a candlestick. Lulu was recently released. Shadybrook is on the same road as Lookout Point.

Sonny's Coffee Shop
This coffee shop was opened in December 2006 by Sonny Corinthos to serve as a front for his illegal activity. Sonny frequently worked out of an office in the building. Carly Corinthos took over decorating and added a coffee cart. This is where Max Giambetti was demoted to working when he helped Carly. This is where Lorenzo Alcazar had a hit woman hide a gun. Alcazar retrieved the gun, went into Sonny's back office, and held him at gunpoint. Carly walked in and was able to distract Alcazar from shooting Sonny. Sonny took this chance and shot Alcazar in the head. On November 14, 2008, Sasha Donev sent a gang of goons to trash the coffeehouse and torch it. Little did they know, as the coffeehouse burned, Olivia Falconeri was trapped in the back in Sonny's office. Sonny managed to save her, but the building was burnt to the ground. Jason is currently having the shop rebuilt.

Wyndemere Castle/Spoon Island
Cassadine family home. The island was leased to the Cassadines long ago by the Native American group. The Cassadines only actually own the actual land that Wyndemere sits on. This island is a popular place for family outings. It is also home to a grand old mansion called Wyndemere, where many noteworthy residents have resided, including Ned Ashton, Cesar Faison, and most currently the Cassadines. Unfortunately, Wyndemere may not be all that safe; it contains many secret passages and underground tunnels, making it an easy target for intruders - Luke Spencer, in particular. This location is above several cliffs. Helena Cassadine pushed Katherine Bell off the parapet, causing her death. Darius, a man hired by Stefan Cassadine pushed Summer Holloway to her death who Darius had mistaken for Emily Quartermaine. Luke Spencer pushed Stefan Cassadine to his death as well. In 2007, madman Anthony Zacchara crashed a masquerade ball being held at Wyndemere and stalked the guests, in the process injuring Ric Lansing with a sword and killing a servant with an ice pick. To make matters even worse, a storm has stranded the guests on the island and caused a power failure. During the night of terror, Emily Quartermaine was strangled. In October 2008, Jasper Jacks attempted to buy Wyndemere out from under Nikolas. He finally succeeded in December, and had planned to build a resort around Wyndemere. Carly managed to turn the war over, and Jax gave Nikolas the lease back. Wyndemere is considered a castle by many, but Nikolas is quick to defend that is a 'mansion'.

ADZ Warehouses
A chain of warehouses owned by the mafia members in the "Tumble Dry" money laundering scam.

Asian Quarter
The Asian Quarter is a ghetto district located within Port Charles and is home to a large Asian population. The residents of this part of the city once lived in fear of an extortion ring that dominated the area, but thanks to the efforts of then police commissioner Robert Scorpio, the extortion ring was busted.

Bamboo Bar
A small bar owned by Wu in the Asian Quarter. Has a secret soundproof room where Robin Scorpio and The Ancient One were being held by Wu's people during the Asian Quarter - Black Pearls storyline.

Barney's Place
A downtown bar where in 1976, Jeff Webber attempted to commit suicide after finding out his wife, Monica Bard, had been having an affair with his brother, Rick.

The Campus Disco
This popular establishment was run by Luke Spencer from 1979 - 1980. It closed in 1981 as Disco music went out of style. This is also where Luke Spencer raped his future wife Laura Webber Baldwin.

The Cellar
Located at 324 Wharf Street, Port Charles, NY– Carly Corinthos, proprietor. Opened February 14, 2003. Rekindled night club created from the remnants of “The Flynn’s Club”, a speakeasy that originally opened New Years Eve 1926. Flynn’s was owned by Catherine Flynn, the grandmother of Faith Rosco. On New Year's Eve 2002, Carly and Ric Lansing discovered the speakeasy bricked off in the basement of Kelly’s Diner when they were scouting for a location for her club. The original owner, Catherine Flynn, who had been living in an apartment across the street, told Carly and Ric the club’s history when she observed them breaking through the brick wall. Employees have included Courtney Matthews as hostess. In November 2003, Faith Rosco claimed ownership of the club stating that though Kelly’s Diner and The Cellar occupied the same building, they always had split deeds and while Luke and Bobbie Spencer owned Kelly’s, The Cellar was rightfully Faith’s property by way of inheritance from Catherine. In May 2004, Carly regained control of the club when Justus Ward discovered that Faith’s claim on the property was invalid. Just prior to her hospitalization in Shadybrook in 2005, she closed the club until she was well again. After recovering, she opted to keep The Cellar closed permanently, stating that it took too much time and money to run.

In April 2007, Sonny and Jason begin to consider using The Cellar as a place to hide their shipments, as The Cellar was vacant at the time. Sonny and Jason were soon ambushed by Lorenzo Alcazar's hired thugs.

Club 101
Elegant night club opened in 2002 by Carly Corinthos with Jasper “Jax” Jacks. The club was converted from an old abandoned warehouse on the “bad side of town” under Carly’s supervision. Jax forced Carly out of the partnership due to what Carly because he believed she was embezzling funds, though she believed it was because of her relationship with Sonny Corinthos. He then brought Skye Chandler Quartermaine in as a partner. Employees have included Courtney Matthews.

The Croydon Hotel
Low cost hotel that was run in Port Charles during the 80's. Residents include Laura Templeton, and her sister Jakie. It was demolished in the early 90's.

Deception
Deception Cosmetics: Former CEO-Laura Spencer; Partner-Carly Corinthos; Former models-Brenda Barrett and Gia Campbell.

Delafield's
Club owned and operated by classical pianist Katherine Delafield. Katherine regularly performed as well as did Frisco Jones. This same club had belonged to Duke Lavery and was purchased after his death in 1990.

Donley Shipping
Shipping company once owned by Sean Donley. Formerly managed by Felicia Jones. Former employees include Anna Devane.

Duke's Club
Run by Duke Lavery and Felicia Jones, this club was a popular hangout for Port Charles residents in the late 1980s. Frisco Jones and Terri O'Connor regularly performed. After Duke's death, the club was purchased in 1990 by classical pianist Katherine Delafield and reopened under the name Delafield's.

The Equinox Corporation
Equinox, officially named the Equinox Defense Arms Corporation was a military equipment manufacturer that was first introduced in January 2007. Exquinox manufactured the armored suitcase that lead to the Metro Court Hostage crisis in February 2007. In November 2008, Nadine Crowell and Nikolas Cassadine took them on in order to get back her Aunt Raylene's plow patent. In January 2009, an Equinox airborne biotoxin was released into General Hospital, forever garnering the label of failure.

Fisherman Village
Waterfront development constructed by mobsters in the “Tumble Dry” money laundering scam. Dan Rooney, Commissioner of Waterfront Development, tried to oppose the construction due to the shoddy construction plans, but was silenced in an “accident” arranged by Mr. Big (Co-Police Chief Burt Ramsey).

The Floating Rib
This restaurant, located across the street from General Hospital, was another popular establishment in the early 1980s. Closed during the late 1980’s. On February 23, 2006, Holly Sutton (not knowing that the restaurant was long out of business) demanded that Luke Spencer and Robert Scorpio meet her outside the restaurant with two million dollars for each vial of antidote for the mutant encephalitis virus that had gripped the city that month. A popular massage parlor is now located on this site.

Flynn's Club/The Cellar
A speakeasy that opened on New Years Eve 1926 beneath what is now Kelly’s Diner. The club was owned by Catherine Flynn, wife of mobster Marco Flynn. It was only open for a few hours because at 12:01 A.M. on opening night, a close friend and associate was killed in the club in a mob hit. Marco retaliated that night, but was arrested. He spent the rest of his life in prison. Catherine never had the heart to reopen, and had it boarded up. The club was discovered in 2002 when Carly Corinthos was looking for a location to open a club of her own. She refurbished this speakeasy and reopened it as “The Cellar”.

HTI
A research firm that the WSB had contracted with to find a secret antidote to the DVX's lethal germ MOX 36. The research was conducted by Dr. Eric Ingstrom before being abducted by the DVX. Stockholders in this firm included Greta Ingstrom and various Quartermaines.

Jacks Cosmetics
Jacks Cosmetics: Original founder: Jasper Jacks; Former CEO: Lucy Coe; Other Known Employees: Brenda Barrett (Former Model)

L&B Records
Record label founded by Lois Cerullo and Ned Ashton. Co-owned at one time by Brenda Barrett and Sonny Corinthos. In 1996, control was seized from Lois and Brenda in a purchase by Edward Quartermaine. Lois regained control with the help of Jasper Jacks. Investors have included Lorenzo Alcazar. Vocalists have included Juan Santiago, Brook Lynn Ashton, Mary Mae Ward and Sage Alcazar. Employees included Kristina Cassadine as an assistant to Ned, Dillon Quartermaine as video director, and Nikolas Cassadine as public relations representative.

Luke's Club
This blues club, run by Luke Spencer and Lucy Coe was a popular place to hangout and socialize during the late 1990s. Lily Corinthos was blown up in a car bomb outside the premises in 1996.

Luke's Place
Port Charles' first casino opened by Luke Spencer and D. L. Brock in 1983. This is notable because according to the city charter, only one casino was allowed to operate. After closing the casino when he was elected mayor later that year, he retained the casino rights. Port Charles did not have another casino until he converted his recently reacquired Haunted Star into a casino on December 26, 2003.

The Oasis
Strip club owned by Coleman where Courtney Matthews secretly worked under the name “Daisy” to pay for damages caused by her then husband, A.J. Quartermaine. On August 28, 2002, A.J. destroyed the club in an arson fire after he found out about Courtney’s job.

The Outback
Popular club once owned and operated by Mac Scorpio. Opened in 1991, Connor Olivera managed the club and worked as a singer. In 1992, Bill Eckert became co-owner. Felicia Jones later bought half ownership of the club, and the two married in 1998, making the club a family business. Employees have included Holly Scorpio, Miguel Morez and Robin Scorpio.

The Paradise Lounge
Strip club once owned by Sonny Corinthos. Karen Wexler and Tammy Hansen once worked there as strippers. The club was closed by the PCPD in 1993 for working underage strippers. The phone number was 555-1081.

The Port Charles Hotel
Elegant hotel that stood at 1420 Courts Lane. It was purchased by the Quartermaines in 1993, but was burnt to the ground on February 11, 2004. The Metro Court Hotel was built on the cleared site.

The Recovery Room
Bar & Grill located across the street from General Hospital. Managed by the Scanlon family and Mary Scanlon's husband Victor Collins. Previously managed by Mike Corbin. Popular establishment in the late 1990s.

Rive Gauche
Posh, upscale Italian restaurant in downtown Port Charles. Johnny Zacchara wanted to take Lulu Spencer here on New Year's Eve 2008.

Tea House
Nice Chinese restaurant run by Jade Soong. Where friends could meet up, but mostly used by those from the Asian Quarter.

The Ward House
Orphanage started by Mary Mae Ward, named for her son Bradley, a community leader who had died 20 years earlier. Pediatrician Simone Hardy was a volunteer at the home and introduced Mary Mae to Laura Spencer. In 1996, Laura Spencer purchased and operated the orphanage after Mary Mae’s death. Destroyed in an arson fire started by mobster Damian Smith who wanted the land to build a toxic waste incinerator.

World Security Bureau
World Security Bureau (WSB) is an Espionage agency and The nemesis of the WSB was the international organization known as the DVX. One of the WSB's most daring and effective agents was Robert Scorpio who traveled incognito as an international financier and well-know bon vivant. During the 1981 season Scorpio tracked down the Ice Princess, a statue/diamond with a secret formula on its base that as Scorpio warned "could cause cataclysmic global problems" if not recovered. On the trail of this huge uncut diamond, WSB agent O'Reilly, an elderly woman, was killed in a shoot out on the docks. Scorpio was helped by Luke and Laura as all three stowed away aboard a yacht to a tropical island that was the base of mad scientist Mikkos Cassadine who wanted exploit the power of the Ice Princess formula to be "Supreme Commander of the World." Mikkos fell to his death in freezing chamber of a machine designed to freeze the world. With the help of Luke, the machine's code (I-C-E-P-R-I-N-C-E-S-S) was cracked, disaster was averted and democracy was restored to the planet. Scorpio became a recurring character on General Hospital.

The Nurses Ball
From 1994 - 2001, the Nurses Ball was the social event of the year in the Port Charles calendar and is most notable for being a charity event dedicated to raising funds for various HIV/AIDS organizations, both on the show and in reality. The Nurses Ball was held in the Port Charles Hotel (which burned down in 2004). Notably from 1997 until the last ball in 2001, the Nurses ball was usually a major crossover where characters from both Port Charles and  General Hospital got a chance to interact with one another. A train/bus collision interrupted the 2001 event. The event has since been discontinued. The onscreen reasons for this have not been explained, but it is known that rising expenses and budget cuts in the real world, along with the revamp that was made to Port Charles in 2001 were the reasons why the producers of both General Hospital and Port Charles decided to end the annual event. But in 2006, Carly Corinthos held a similar event in which she auctioned off men to have dinner with women, and all of the money was donated to the hospital.

General Hospital Pediatric Ward Christmas party
For many years, the Pediatric Ward Christmas party has been the focus of General Hospital episodes that have aired just before Christmas (usually on the December 24 episode of General Hospital, but sometimes on December 23 or December 22 if December 24 falls during a weekend). It is traditional for the current chief of staff to read the Christmas story to the children during the party. The chief is also accompanied by the General Hospital volunteers dressed up as Mr. and Mrs. Claus, as well as elves. The children of various cast members from the show are often featured as extras in the party scenes playing the sick children from the ward.

The Webbers and Hardys
Steve Hardy was the chief of Staff at General Hospital from the mid 1970s until his death in 1996. Perhaps one of Dr Hardy's biggest achievements was finding a cure to the Lassa Fever epidemic of 1979. He was married to Audrey Hardy for many years, and adopted her son Tom Hardy, who would also become a doctor. His other son, Jeff Webber, is a doctor as well. Jeff's eldest children, Steven and Sarah, are also doctors, while his youngest daughter, Elizabeth, is a nurse. Elizabeth has two children, Cameron Spencer, whom she is raising with Lucky Spencer and Aiden Spencer her biological son with Lucky. She also had another son Jake Spencer whom she also raised with Lucky, but Jake was killed in a hit and run car accident.

The Quartermaines
One of the most distinguished families in Port Charles is the Quartermaine family, who moved to the area in 1978 and are best known for running E.L.Q. Industries. The Quartermaines have had a long-standing rivalry with Sonny Corinthos that began when Sonny married Carly Roberts, the former wife of A.J. Quartermaine and forced A.J. to give up parental rights to his and Carly's son Michael. Dr. Alan Quartermaine was the chief of staff at General Hospital, while his wife Monica is a renowned heart surgeon. Rock star Eddie Maine is also a prominent member of this family. Other Quartermaine's include Tracy Quartermaine, Emily Quartermaine, Skye Quartermaine, Justus Ward, Dillon Quartermaine, Brook Lynn Ashton, and Jason Morgan.

The Spencers: Luke and Laura Webber Spencer
Laura Webber first gained notoriety in the infamous David Hamilton murder case in 1978. Only sixteen at the time, she had begun an affair with the much older David Hamilton only to murder him when she found out he was using her to get back at her mother. Laura escaped a jail sentence due to the extenuating circumstances of the crime, but her reputation as a murderess was notorious throughout the town. Later though, Laura would gain fame in a more positive way when she helped her future husband Luke Spencer defeat the evil schemes of both Frank Smith and Mikkos Cassadine. The two would then marry in a ceremony held on the lawn of the mayor's mansion. Sadly, Luke and Laura would later divorce and Laura suffered a mental breakdown in 2002, leading to her incarceration in a psychiatric facility. Laura was given and experimental drug "LS49" in October 2006. The drug brought her out of her catatonic state, but sadly the drug's effects were only temporary. While Laura was back with her family she and Luke were married again on their 25th anniversary, November 16, 2006.

Luke Spencer is possibly the most famous resident of Port Charles (and also one of its most flamboyant). Luke Spencer first gained notoriety when he, along with his future wife Laura Webber, helped bust the Frank Smith mafia gang in 1980. The following year, Luke was instrumental (again along with his wife Laura and future police commissioner Robert Scorpio) in foiling the plans of Mikkos Cassadine, a madman who had frozen Port Charles in order to showcase his weather machine. Luke and Laura married on the lawn of the mayors mansion in November 1981 in what was possibly the biggest wedding Port Charles has ever seen. Luke later ran for mayor of Port Charles in 1983 and won, but resigned less than two months into his tenure in order so that he and Laura could leave town to travel the world. Luke and Laura later returned to Port Charles in 1993.

Luke and Laura have two children together, Lucky Spencer and Lulu Spencer. Laura also has a son with Stavros Cassadine, Nikolas Cassadine. It had also been reveled that Luke shares a son with Holly Sutton, named Ethan Lovett. Lucky has a biological son Aiden Spencer with Elizabeth Webber and is raising Elizabeth's other son, Cameron Spencer, as his own. Lucky also raised Elizabeth's second child Jake Spencer as his own, but Jake was killed in a hit-and-run fewer than two months before his fourth birthday.

The Cassadines
The Cassadine brothers, Mikkos, Tony and Victor first made their presence in Port Charles felt in 1981, when they caused the infamous blizzard through the use of carbonic snow. Mikkos' younger son Stefan eventually took control of the family and in 1996, he and his nephew Nikolas moved to Port Charles permanently, joined by distant Cassadine cousin Alexis Davis who was later revealed to be Mikkos' illegitimate daughter (Natasha Cassadine) with Swedish opera singer Kristen Bergmen. For a time, Stefan owned General Hospital. Stefan's older brother Stavros Cassadine who had previously died, had kidnapped Laura Spencer and together they had Nikolas, before she escaped leaving Nikolas with Stefan. In 2001, the family received another addition when Alexis' long lost sister, Kristina Cassadine (originally Kristina Carter), was brought to town to reunite with her sister by Jasper Jacks. Stefan later died in 2003, but Nikolas remains in the city. From time to time, Nikolas' grandmother Helena, the widow of Mikkos shows up to terrorize various residents of the city. Alexis has given birth to three daughters, Samantha McCall, Kristina Davis, and Molly Lansing. Nikolas now has a child, Spencer Cassadine, with the late Courtney Matthews. Samantha McCall had a daughter Lila McCall with Sonny Corinthos but Lila was stillborn on November 8, 2004.

The Scorpios
Australian ex-pat Robert Scorpio was Police Commissioner of Port Charles for many years (1982-1985, 1987-1992), and solved numerous mysteries and crimes. Robert was presumed dead in 1992, but later returned to town in 2006 to track down Luke Spencer who had brought the encephalitis outbreak to Port Charles. Now trying to mend his relationship with his daughter and his wife, Robin and Anna Devane. Mac Scorpio is Robert's brother, and Mac has two adopted daughters Maxie Jones and Georgie Jones (deceased). The newest member of the Scorpio family is Robin's daughter with Patrick Drake, Emma Scorpio-Drake.

The Mob: Sonny Corinthos and Jason Morgan
Sonny Corinthos arrived in Port Charles in 1993, and owned and operated a strip club before becoming Port Charles' most powerful mobster in the power struggles that followed Frank Smith's death. Sonny has become known for his relative benevolence compared to other mafia gangs and his donation of several million dollars was instrumental in setting up the Stone Cates Memorial Wing at General Hospital.

Everybody in Port Charles knows who Jason Morgan is. He was born into wealth as Jason Quartermaine, the son of Dr. Alan Quartermaine and his mistress Susan Moore, he was later adopted by Monica Quartermaine. He was well liked, smart, and basically one of the only sane things ever to come out of the Quartermaine family. He was medical student, to follow in the foot steps of his parents, but one fateful night changed all of that. One night when he was trying to stop his brother A.J. Quartermaine from driving drunk he got in the car with him and they crashed leaving Jason permanently brain damaged with no memory of his life. He broke away from his family, changed his last name to Morgan (in honor of his paternal grandmother Lila Morgan Quartermaine), and started working for mobster Sonny Corinthos. Over time Jason has gotten closer to his family, especially his adopted-sister Emily Quartermaine and his adopted mother Monica Quartermaine. In April 2008 Sonny Corinthos signed over the entire Corinthos-Morgan Crime family to Jason Morgan after his son was shot. Sonny was trying to escape the dangerous life for his son (Morgan) his daughter (Kristina) and his then fiance, Kate Howard. In March 2009, Jason gave the business back to Sonny.

Past and current members and employees/affiliates of the Corinthos-Morgan crime family are Sonny Corinthos, Jason Morgan, Carly Jacks, Brenda Corinthos, Sam McCall, Robin Scorpio, Courtney Matthews, Damian Spinelli, Claudia Zacchara, Justus Ward, Ric Lansing, Diane Miller, Max Giambetti, Milo Giambetti, Cody Paul, Cooper Barrett, Logan Hayes, Johnny Zacchara, Dominic Parelli, Richie, Bernie Abrahms, and Benny Abrahms.

The Zaccharas
Insane mob boss, Anthony Zacchara came to Port Charles in September 2007. He brought his son, Johnny Zacchara and his lawyer, Trevor Lansing. It turned out that Trevor was the real mob boss. When Anthony jumped off the roof of Wyndemere Castle, he was paralyzed from the neck down and his son Johnny became the new mob boss. Johnny has plans to take down a manipulative Trevor. Claudia Zacchara who is Johnny's sister arrived in Port Charles on January 31.

Estates

 * Quartermaine Mansion (66 Harbor View Road) - Monica Quartermaine, Edward Quartermaine, Tracy Quartermaine-Spencer and Alice Gunderson
 * Greystone Manor (120 Shoreline Road) - Sonny Corinthos, Max Giambetti, and Milo Giambetti
 * Jacks Lake House (657 Harbor View Road) - Carly Benson, Morgan Corinthos and Josslyn Jacks
 * Howard Estate (124 Shoreline Road) - Kate Howard

Houses

 * Davis Home (55 Cherry Lane) - Alexis Davis, Kristina Corinthos-Davis, and Molly Lansing-Davis
 * Scorpio-Drake Home (Queen's Point suburb) - Robin Scorpio, Patrick Drake and Emma Scorpio-Drake
 * Webber Home (458 Lexington Avenue, Queen's Point suburb) - Elizabeth Webber, Cameron Spencer and Aiden Spencer
 * The Brownstone (1224 Elm Street) - Bobbie Spencer
 * Hardy House (453 Maple Avenue) - Audrey Hardy

Penthouse Apartments/Lofts

 * Winslow Garden Apartments (114 Clover Avenue), Apartment 68 - Maxie Jones and Lulu Spencer
 * Johnny's Penthouse Apt. (344 West Adams) - Johnny Zacchara and Anthony Zacchara
 * Harborview Towers (122 Harbor View Drive), PH #2 - Jason Morgan, Sam McCall, and Damian Spinelli
 * Sam's Loft (#346) - Sam McCall
 * Olivia's Condo (#3) - Olivia Falconeri
 * Dante's Loft, Apt. #4B - Dante Falconeri
 * Abby's Apt. (827 Emerson, Apartment 3-C) - Abby Haver and Michael Corinthos
 * Lucky's Apt. ('27 S. Patton, Apt 2B) - Lucky Spencer and Siobhan McKenna

Other Residences

 * The Haunted Star (yacht) - Luke Spencer and Ethan Lovett
 * The Island (The Bahamas) - The frequent vacation home of Sonny Corinthos.

Estates

 * Quartermaine Mansion (66 Harbor View Road) - Former residence of Lila Quartermaine, Alan Quartermaine, Dillon Quartermaine, Skye Quartermaine, Jason Morgan, Emily Quartermaine, Ned Ashton, Carly Corinthos, Michael Corinthos, Lulu Spencer, A.J. Quartermaine, Dawn Winthrop, Karen Wexler, Georgie Jones, Katherine Bell, Brook Lynn Ashton, Justus Ward, Chloe Morgan, Brenda Barrett, Lois Cerullo, Luke Spencer, Ethan Lovett and Maya Ward.
 * Greystone Manor (120 Shoreline Road) - Former residence of Brenda Corinthos, Alec Scott, Carly Corinthos, Morgan Corinthos, Michael Corinthos, Reese Marshall, Claudia Zacchara, Jason Morgan, Sam McCall, Emily Quartermaine, and Leticia Juarez.
 * Alcazar Estate (243 Sky Cliff Road) - Former residence of Carly Corinthos, Lorenzo Alcazar, and Michael Corinthos
 * Zacchara Mansion (257 Cardinal Drive) - Former residence of Anthony Zacchara, Claudia Zacchara, Johnny Zacchara, and Trevor Lansing
 * Wyndemere Castle - Former residence of Nikolas Cassadine, Spencer Cassadine, Helena Cassadine, Colleen McHenry, Emily Quartermaine, Ned Ashton, Stefan Cassadine, Cesar Faison, Katherine Bell, Gia Campbell, Lydia Karenin, and Rebecca Shaw, Elizabeth Webber, Cameron Spencer, Jake Spencer, Aiden Spencer and Brook Lynn Ashton.
 * Jacks Lake House - Former residence of Jasper Jacks and Michael Corinthos.

Houses

 * 13 King Street - Former residence of Lesley Webber
 * Spencer Home (formerly the Ward Home) (24 Royal Street) - Former residence of Laura Spencer, Luke Spencer, Lesley Webber, Lulu Spencer, Elizabeth Webber, Lucky Spencer, Cameron Spencer, Mary Mae Ward, Dan Ward, Bradley Ward, David Ward, and Idios Ward.
 * Lansing Home (55 Cherry Lane) - Former Residence of Elizabeth Webber and Ric Lansing.
 * Lavery Home (309 Baptiste Way) - Former residence of Duke Lavery and Anna Devane
 * Hardy House (453 Maple Avenue) - Former residence of Elizabeth Webber, Sarah Webber, and Steve Hardy
 * Jacks Home (607 Broadroad Terrace) - Former residence of Jasper Jacks, Carly Corinthos, Morgan Corinthos, and Michael Corinthos
 * Baldwin Home (777 Douglas Street) - Former residence of Scott Baldwin and Serena Baldwin
 * Scorpio Home (1020 North Yale) - Former residence of Mac Scorpio, Maxie Jones, Georgie Jones, Felicia Jones, Robin Scorpio, Rachel Adair, Brook Lynn Ashton, Matt Hunter, and Emma Scorpio-Drake

Penthouse Apartments/Lofts

 * Winslow Garden Apartments (114 Clover Avenue) - Former residence of Johnny Zacchara
 * Harborview Towers (122 Harbor View Drive) - Former residence of Justus Ward, Jason Morgan, Courtney Matthews, Brenda Barrett, Carly Corinthos, Sonny Corinthos, Stone Cates, Alexis Davis, Kristina Cassadine, Sam McCall, Michael Corinthos, Morgan Corinthos, and Reese Marshall
 * Ashton Loft (321 Harbor View Road) - Former residence of Ned Ashton, Alexis Davis, and Lois Cerullo
 * Jones Apt. (2790 Bristol Street: Apartment 3E) - Former residence of Tony Jones and Tania Roskov

Other Residences

 * Kelly's Diner (324 Wharf Street) - Former residences include Holly Sutton, Jimmy Lee Holt, Celia Quartermaine, Felicia Jones, Edward and Lila Quartermaine, Lily Corinthos, Brenda Barrett, Jason Morgan, Sam McCall, Miguel Morez, Juan Santiago, Courtney Matthews, Emily Quartermaine, Keesha Ward, Ric Lansing, Lucky Spencer, Diego Alcazar, Javier Ruiz, Elizabeth Webber, Maxie Jones, Dillon Quartermaine, Georgie Jones, Coop Barrett, Rebecca Shaw, and Tammy Hansen
 * 860 Birch Tree Lane - Former residence of Brenda Barrett, Jason Morgan, Emily Quartermaine, and Zander Smith
 * 1242 Elm Street -Former residence of Lucas Jones, Felicia Jones, Georgie Jones, Maxie Jones, Frisco Jones, and Marcus Taggert
 * The Ianai (Maui, Hawaii) - Former residence of Jason Morgan and Sam McCall.
 * The Croydon Hotel: Suite 1775 - Former residence of Laura Templeton
 * Lazarus Yachts I and II - Former residence of Sam McCall
 * Haunted Star Yacht: Suite C3 - Former residence of Dillon Quartermaine and Georgie Jones
 * Haunted Star Yacht: Suite A1 - Former residence of Luke Spencer

Metro Court Suites

 * Metro Court Hotel: Suite 421 - Former residence of Jerry Jacks
 * Metro Court Hotel: Suite 421 - Former residence of Nikolas Cassadine
 * Metro Court Hotel: Suite 423 - Former residence of Garrett Floyd
 * Metro Court Hotel: Suite 433 - Former residence of Robert Scorpio
 * Metro Court Hotel: Suite 483 - Former residence of Max Giambetti
 * Metro Court Hotel: Suite 487 - Former residence of Diane Miller
 * Metro Court Hotel: Suite 633 - Former residence of Reese Marshall
 * Metro Court Hotel: Suite 718 - Former residence of Anna Devane
 * Metro Court Hotel: Suite 819 - Former residence of Courtney Matthews
 * Metro Court Hotel: Suite 917 - Former residence of Holly Sutton
 * Metro Court Hotel: Suite 1205 - Former residence of Olivia Falconeri
 * Metro Court Hotel: Suite 1220 - Former residence of Carly Corinthos
 * Metro Court Hotel: Suite 5529 - Former residence of Patrick Drake
 * Metro Court Hotel: Suite 6305 - Former residence of Jasper Jacks
 * Metro Court Hotel: Suite 6305 - Former residence of Johnny Zacchara
 * Metro Court Hotel: Suite 6306 - Former residence of Anthony Zacchara

Port Charles Hotel Suites

 * Port Charles Hotel: Suite 174 - Former residence of Justus Ward
 * Port Charles Hotel: Suite 213 - Former residence of Damian Smith
 * Port Charles Hotel: Suite 244 - Former residence of Mike Corbin
 * Port Charles Hotel: Suite 347 - Former residence of AJ Quartermaine
 * Port Charles Hotel: Suite 683 - Former residence of Alexis Davis
 * Port Charles Hotel: Suite 753 - Former residence of Faith Rosco
 * Port Charles Hotel: Suite 778 - Former residence of Ned Ashton
 * Port Charles Hotel: Suite 885 - Former residence of Frisco Jones
 * Port Charles Hotel: Suite 918 - Former residence of Jasper Jacks
 * Port Charles Hotel: Suite 987 - Former residence of Luis Alcazar
 * Port Charles Hotel: Suite 992 - Former residence of Katherine Bell
 * Port Charles Hotel: Suite 915 - Former residence of Skye Chandler

Mayors

 * Quinn Waser (1969-1974)
 * Bruce Jennings (1974-1979)
 * John Everett (1979-1980)
 * Luke Spencer (1983)
 * Lee Baldwin (1983-1985)
 * Ken Morgan (1985-1989)
 * Earl Richmond (1989-1993)
 * Tom McClintock (1997-2001)
 * Riley Dowd (2001-2006)
 * Garrett Floyd (2006-present)

Council Members

 * Casslyn Verga (1986-1991)
 * Dover (1992)
 * Jerry Perez (1994-1996)
 * Blake (1994)
 * Bradley Ward (1994)
 * Clemens (1995)
 * A.J. Quartermaine (1997)
 * Raymond (2009)

Police Department

 * Captain Patterson (1963-1974)
 * Captain Wendell (1974-1979)
 * Police Captain Burt Ramsey (1979-1983)
 * Police Commissioner Robert Scorpio (1983-1985, 1988-1992)
 * Co-Chief of Police Anna Devane (1985-1986)
 * Co-Chief of Police Burt Ramsey (1985-1986)
 * Chief of Police Anna Devane (1986-1987)
 * Chief of Police Guy Lewis (1987-1992)
 * Police Commissioner Sean Donely (1992-1995)
 * Police Commissioner Mac Scorpio (1996-2000, 2000-present)
 * Detective Joe Kelly
 * Detective Frisco Jones
 * Detective Andy Garcia
 * Detective Andy Capelli (2001-2004)
 * Detective Lucky Spencer (2003-present)
 * Police Officer Byron Murphy (2004-2005)
 * Detective Jesse Beaudry (2005-2006)
 * Detective Cruz Rodriguez (2005-present)
 * Intern Sam McCall (2006)
 * Detective David Harper (2007-present)
 * Police Cadet Cooper Barrett (2007-2008)
 * Special Prosecutor Scott Baldwin (2007-2008)
 * Detective Dante Falconeri (2010-present)
 * Detective Ronnie Dimestico (2010-present)

District Attorneys

 * Chase Murdoch (1966-1971, 1973-1979)
 * Mitch Williams (1979-1980)
 * Bill Richardson (1982-1983)
 * Mick Boyer (1984)
 * Ken Morgan (1984-1985)
 * Brett Madison (1986)
 * D.A. Lombardi (1986)
 * Michael Shultz (1990)
 * Abbey Mitchell (1993)
 * Justus Ward (1998)
 * Scott Baldwin (2002-2004)
 * Ric Lansing (2004-2005, 2006-2008)
 * John Durant (2005-2006)
 * Alexis Davis (2005-2006, 2008-2009)
 * Interim D.A. (2009-present)

Assistant District Attorneys

 * Xavier Coons (1967-1973)
 * Ross Jenelle (1974)
 * Mitch Williams (1978)
 * Scott Baldwin (1988)
 * Jessica Holmes (1992)
 * Dara Jensen (1996-2003)
 * Ric Lansing (2004)
 * Alexis Davis (2006)
 * Job Eliminated (2006-2009)
 * Louise Addison (2009-present)

Legal Facilities

 * Port Charles Police Department
 * Pentonville Penitentiary
 * Statesville Prison
 * Port Charles Courthouse
 * Port Charles City Hall
 * Mason, Petrovich, and Miller Law Firm

Transportation

 * Port Charles Airport
 * Star Fall (airline charter)
 * Slick's Taxi Service

Education

 * Winston School - Molly Lansing, Kristina Corinthos (former)
 * Madison Prep - Former students include Kristina Corinthos, Michael Corinthos, and Kiefer Bauer
 * Queen of Angels - Morgan Corinthos, Michael Corinthos III (former)
 * Port Charles High School - Former students include Lulu Spencer, Lucky Spencer, Elizabeth Webber, Emily Bowen-Quartermaine, Sarah Webber, Nikolas Cassadine, Georgie Jones, Maxie Jones, and Lucas Jones
 * Port Charles University (PCU) - Dr. Pete Marquez (professor), former students include Lulu Spencer, Maxie Jones, Georgie Jones (at time of death), Diego Alcazar, Lucas Jones, Dillon Quartermaine, Robin Scorpio, Damian Spinelli, Felicia Jones and Jade Soong.

Religion

 * St. Timothy's Church - Father Coates
 * Queen of Angels Church
 * General Hospital Chapel
 * Sailor's Chapel
 * St. Anne's Cemetery

Medical

 * General Hospital
 * Mercy Hospital
 * County Hospital
 * Emily Bowen Quartermaine Memorial Clinic
 * Roselawn Sanitarium
 * Shadybrook Sanitarium
 * Ferncliff Asylum
 * Port Charles Women's Clinic

Chief Of Staff

 * Dr. Bryant Nemer (1966-1971)
 * Dr. Anderson Valey (1971-1976)
 * Dr. Steve Hardy (1976-1996)
 * Dr. Alan Quartermaine (1996-1998)
 * Dr. Monica Quartermaine (1998-1999)
 * Dr. Alan Quartermaine (1999-2007)
 * Dr. Russell Ford (2007-2008)
 * Dr. Patrick Drake (2008; interim)
 * Dr. Monica Quartermaine (2008-2009)
 * Dr. Patrick Drake (2009; interim)
 * Dr. Steven Webber (2009-2011)
 * Dr. Robin Scorpio-Drake (2011-present; interim)

Assistant Chief of Staff

 * Dr. Perry Masil (1966-1970)
 * Dr. Wendel Eltoz (1970-1975)
 * Dr. Buzz Stryker (1985-1987)
 * Dr. Monica Quartermaine (1987-1988)
 * Dr. Alan Quartermaine (1988-1990)
 * Dr. Tom Hardy (1990)
 * Position eliminated (1990)

Head Nurse

 * Lucille March (1963-1976)
 * Audrey Hardy (1976-2006)
 * Epiphany Johnson (2006-present)

Other Personnel

 * Dr. Rachel Adair (pediatrician, former)
 * Sage Alcazar (candy striper, former)
 * Dr. Andy Archer (anesthesiologist, former)
 * Dr. Gail Baldwin (psychiatrist, former)
 * Dr. Saira Batra (doctor specializing in Holistic health, former)
 * Melissa Bedford (nurse, former)
 * Carly Benson (physical therapist, former)
 * Meg Bentley (nurse, former)
 * Dr. Phil Brewer (former)
 * Jessie Brewer (nurse, former)
 * Dr. Ellen Burgess (former)
 * Florence Campbell (administrator, former)
 * Nikolas Cassadine (CEO)
 * Stefan Cassadine (CEO, former)
 * Dr. Ryan Chamberlain (pediatrician, former)
 * Betsy Chilson (nurse, former)
 * Dr. Yank Se Chung (former)
 * Judy Clampett (nurse, former)
 * Dr. Kevin Collins (psychiatrist, former)
 * Jolene Crowell (nurse, former)
 * Nadine Crowell (nurse, former)
 * Howie Dawson (administrator, former)
 * Jane Dawson (nurse, former)
 * Dr. Mark Dante (former)
 * Dr. Ian Devlin (former)
 * Dr. Pierce Dorman (physician, former)
 * Dr. Noah Drake (neurosurgeon, former)
 * Dr. Patrick Drake (neurosurgeon)
 * Toussaint Dubois (janitor, former)
 * Iris Fairchild (nurse, former)
 * Dr. Irma Foster (head of psychiatry, former)
 * Audrey Hardy (nurse, former)
 * Dr. Steve Hardy (internist, former)
 * Dr. Simone Hardy (pediatrician, former)
 * Dr. Tom Hardy (psychiatrist, former)
 * Dr. James Hobart (former)
 * Dr. Matt Hunter (neurosurgeon)
 * Dr. Terrell Jackson (pediatric surgeon)
 * Georgie Jones (candy striper, former)
 * Maxie Jones (candy striper, former)
 * Tania Jones (speech therapist, former)
 * Dr. Tony Jones (neurosurgeon, former)
 * Dr. Leo Julian (former)
 * Cassius Kibideaux (orderly, former)
 * Dr. Kelly Lee (OB/GYN)
 * Dr. Cameron Lewis (psychiatrist, former)
 * Camillia McKay (nurse, former)
 * Augusta McLeod (nurse, former)
 * Leyla Mir (nurse, former)
 * Miguel Morez (orderly, former)
 * Dr. Lisa Niles (orthopedic surgeon, former)
 * Dr. Kevin O'Connor (former)
 * Dr. Patrick O'Connor (former)
 * Dr. Henry Pinkham (former)
 * Sharon Pinkham (nurse, former)
 * Dr. John Prentice (OB/GYN, former)
 * A.J. Quartermaine (orderly, former)
 * Dr. Alan Quartermaine (physician, former)
 * Emily Quartermaine (intern, former)
 * Dr. Monica Quartermaine (cardiologist)
 * Dan Rooney (administrator, former)
 * Dr. Robin Scorpio-Drake (neuropathologist)
 * Rebecca Shaw (x-ray technician, former)
 * Claire Simpson (intern, former)
 * Iris Sneed (administrator, former)
 * Bobbie Spencer (surgical nurse)
 * Dr. Buzz Stryker (former)
 * Diana Taylor (nurse, former)
 * Dr. Peter Taylor (psychiatrist, former)
 * Dr. Asher Thomas (former)
 * Amy Vining (nurse, former)
 * Keesha Ward (worked in the Social Work Department, former)
 * Maya Ward (intern, former)
 * Elizabeth Webber (surgical nurse)
 * Dr. Jeff Webber (physician, former)
 * Dr. Lesley Webber (physician, former)
 * Sarah Webber (intern, former)
 * Dr. Steven Webber (pediatrician, surgeon)
 * Dr. Karen Wexler (physician, former)
 * Dr. Lainey Winters (psychiatrist)
 * Dawn Winthrop (student nurse, former)

1970s

 * Peggy Nelson - Strangled by Arnold Nelson (1971)
 * Kristen Bergman - Throat slit by Helena Cassadine (1973; Revealed in 2001)
 * Phil Brewer - Bludgeoned with a geode by Augusta McLeod (1974)
 * Bradley Ward - Shot and killed by Jack Boland (offscreen) (1 July 1974; Revealed in 1994)
 * David Hamilton - Accidentally pushed into a fireplace by Laura Webber (1978)
 * Theresa Carter - Hit over the head with a camera by Laura Webber (1978; Revealed in 2002)

1980s

 * Diana Taylor - Accidentally shot and killed by Alice Grant (1981)
 * James Duvall - Pushed down stairs by Alexandria Quartermaine (1981)
 * Brighton O'Reilly - Shot and killed by Victor Cassadine (1981)
 * Alexandria Quartermaine - Inadvertently frozen to death in Mikkos Cassadine's Ice Chamber (1981)
 * Tony Cassadine - Inadvertently frozen to death in Mikkos Cassadine's Ice Chamber (1981)
 * Mikkos Cassadine - Thrown into Ice Chamber by Luke Spencer (1981)
 * Susan Moore - Shot and killed by Crane Tolliver (1983)
 * Crane Tolliver - Shot and killed by Robert Scorpio (1983)
 * Beatrice LeSeur - Overdose of Diazepam (1983)
 * D.L. Brock - accidentally shot and killed by Ginny Blake (1985)
 * Jennifer Talbot - Strangled to death by Kevin O'Connor (1986)
 * Herbert Quartermaine - Poisoned with arsenic by Betsy Quartermaine (1987)
 * Filomena Soltini - Shot and killed by Cesar Faison (1988)

1990s

 * Duke Lavery - Killed in a shootout with Julian Jerome (1990)
 * Dawn Winthrop - Bludgeoned to death with lead pipe by Edge Jerome (1991)
 * Bill Eckert - Shot and killed by Frank Smith's men (November 1993)
 * Jessica Holmes - Stabbed to death by Ryan Chamberlain (1993)
 * Dominique Stanton Baldwin - Inoperable Brain Tumor (1993)
 * Ray Conway - Died of a broken neck after being thrown against a wall by Alan Quartermaine (1993)
 * B.J. Jones - Taken off life support after a bus crash (18 May 1994)
 * Frank Smith - Shot and killed by Luke Spencer (1994)
 * Stone Cates - AIDS related compilations (1995)
 * Paige Bowen - Cancer (1995)
 * Mary Mae Ward - Died of natural causes (January 1996)
 * Damian Smith - Died in an arson fire caused by Justus Ward (1996)
 * Lily Corinthos - Died in a car bombing meant for Sonny Corinthos (3 June 1996)
 * Steve Hardy - Suffered a fatal heart attack (off-screen) (July 1996)
 * Pierce Dorman - Shot and killed by Hernando Rivera (1997)
 * Jake Marshak- Hanged to death by serial killer Greg Cooper (June 1998)
 * Grace Sullivan - Drowned in lake by serial killer Greg Cooper (1998)
 * Katherine Bell - Pushed to her death from a parapet by Helena Cassadine (October 1999)

2000s

 * Cesar Faison - Killed in a boat explosion in Port Charles Harbor, body never recovered (2000)
 * Chloe Morgan - Strangled by Stavros Cassadine (4 September 2001)
 * Stavros Cassadine - Fell to his death in a bottomless pit during a fight with Luke Spencer (November 2001)
 * Kristina Cassadine - Caught in an explosion in Sonny Corinthos's warehouse; died in ICU (August 2002)
 * Rick Webber - Hit over the head with a candle stick by Laura Spencer; actually killed by Scott Baldwin (August 2002)
 * Luis Alcazar - Pushed off a balcony fourteen stories to his death by Alexis Davis (November 2002)
 * Karen Wexler - Fatally hit by car (sometime after 1 January 2003)
 * Catherine Flynn - Poisoned with cyanide by Faith Rosco (28 February 2003)
 * Summer Holloway - Pushed off cliff by Darius Jensen and fell to her death (June 2003)
 * Stefan Cassadine - Stabbed; pushed off a cliff by Luke Spencer and fell to his death (10 October 2003)
 * Dr. Cameron Lewis - Caught under falling debris in Port Charles Hotel fire (19 February 2004)
 * Brian Beck - Shot and killed by Andy Capelli (February 2004)
 * Andy Capelli - Shot and killed in a struggle with Jason Morgan (February 2004)
 * Zander Smith - Shot to death by the S.W.A.T. Team (23 March 2004)
 * Ross Duncan - Buldgeoned with a lead pipe to death by Heather Webber (April 2004)
 * Lila Quartermaine - Died in her sleep (off-screen) (July 2004)
 * Sage Alcazar - Stabbed by Mary Bishop and froze to death in the Quartermaine freezer (25 August 2004)
 * Trent Parker - Stabbed with a garden harrow to death by Mary Bishop (27 August 2004)
 * Mary Bishop - Poisoned with penicillin to death by Lorenzo Alcazar (September 2004)
 * Connor Bishop - Shot to death by Emily Quartermaine in self defense (25 January 2005)
 * Faith Rosco - Shot by Jason Morgan; later died in General Hospital (9 March 2005)
 * A.J. Quartermaine - Suffocated by Dr. Asher Thomas with a pillow (26 April 2005)
 * Evan Tucker - Hit his head on a rock in a fight with Reese Marshall (17 June 2005)
 * Rachel Adair - Lethal Injection of digitalis by Dr. Asher Thomas (27 July 2005)
 * Asher Thomas - Shot and killed by Jason Morgan (8 August 2005)
 * Andrew Domman - Shot and killed by Jason Morgan (August 2005)
 * Javier Ruiz - Shot and killed by Jason Morgan (October 2005)
 * Reese Marshall - Died from a punctured lung in a train crash (14 November 2005)
 * Tony Jones - Died from encephalitis after working tireless hours around the infection (10 February 2006)
 * Courtney Matthews - Died from encephalitis when she was weakened by childbirth (21 February 2006)
 * Daniel McCall - Encephalitis (22 February 2006)
 * Jesse Beaudry - Taken off life support after being shot by Manny Ruiz (31 March 2006)
 * Miguel Escobar - Shot and killed by Jason Morgan (31 March 2006)
 * John Durant - Shot and killed by Manny Ruiz (5 May 2006)
 * Justus Ward - Shot and killed by Manny Ruiz (16 June 2006)
 * Manny Ruiz - Pushed from the roof of General Hospital by Jason Morgan (4 July 2006)
 * Aleksander Janacek - Shot and killed by Brenda Barrett while he was strangling Dante Falconeri (offscreen 2007; shown in flashbacks 2010-2011)
 * Alan Quartermaine - Suffered multiple heart attacks after being held hostage by Jerry Jacks (27 February 2007)
 * Lorenzo Alcazar - Shot and killed by Jason Morgan (22 May 2007)
 * Leticia Juarez - Strangled to death by Diego Alcazar (4 September 2007)
 * Emily Quartermaine - Strangled to death by Diego Alcazar (31 October 2007)
 * Georgie Jones - Strangled to death by Diego Alcazar (17 December 2007)
 * Stan Johnson - Jerry Jacks had him killed (offscreen) (3 January 2008)
 * Coop Barrett - Hanged to death by Diego Alcazar (25 January 2008)
 * Diego Alcazar - Accidentally hanged himself in a struggle with Nikolas Cassadine and Maxie Jones (6 March 2008)
 * Dr. Ian Devlin - Shot and killed by Jason Morgan (5 May 2008)
 * Logan Hayes - Stabbed to death by Lulu Spencer in self defense (8 July 2008)
 * Dr. Russell Ford - Killed by a car that crashed into the ER (22 July 2008)
 * Andrei Karpov - Shot and killed by Sonny Corinthos (7 November 2008)
 * Sasha Donev - Shot and killed by a sniper (19 December 2008)
 * Earl Bragg - Ingested toxic spheres (28 January 2009)
 * Andy Archer - Infected with an airborne poison while performing surgery (29 January 2009)
 * Leyla Mir - Infected with an airborne poison while performing surgery (2 February 2009)
 * Trevor Lansing - Accidentally fell off the roof of General Hospital (13 February 2009)
 * Brianna Hughes - Bludgeoned by Andrea Floyd (12 June 2009)
 * Andrea Floyd - Accidentally ran down by Edward Quartermaine (9 September 2009)
 * Claudia Zacchara - Hit over the head with an axe handle by Michael Corinthos III while she was trying to kidnap newborn Josslyn Jacks (4 November 2009)

2010s

 * Kiefer Bauer - Accidentally ran over by Alexis Davis in a hit and run (6 April 2010)
 * Carter - Stabbed and killed in self defense by Jason Morgan (11 June 2010)
 * Warren Bauer - Shot and killed by Mac Scorpio while Warren was trying to shoot Kristina Corinthos-Davis (23 July 2010)
 * Anton Banavik - Shot and killed by Brenda Barrett while he was trying to kill Dante Falconeri (1 November 2010)
 * Jake Spencer - Taken off life support after sustaining severe irreparable head trauma due to being ran over by Luke Spencer in a hit-and-run car accident (22 March 2011)
 * Theo Hoffman - Throat slit by his wife Suzanne Stanwyck (31 March 2011)
 * Brandon Lowell - Shot in the head by a hitwoman hired by Anthony Zacchara. (April 2011)

Rapes

 * Jessie Brewer - by Phil Brewer (1965)
 * Audrey March Hardy - by Tom Baldwin (1969)
 * Diana Taylor - by Phil Brewer (1973)
 * Monica Quartermaine - by an unknown man (offscreen; prior to 1977)
 * Lesley Webber (1976)
 * Laura Spencer - by Luke Spencer (1979)
 * Laura Spencer - by Stavros Cassadine (1983)
 * Claudia Zacchara - by Trevor Lansing (offscreen; 1991)
 * Carly Corinthos - by Dan Roberts (offscreen; prior to 1996)
 * Elizabeth Webber - by Tom Baker (1998)
 * Emily Quartermaine - by Connor Bishop (2005)
 * Jasper Jacks - by Irina (2007)
 * Michael Corinthos - by Carter (offscreen in 2010; shown in flashback 2011)

Notable Trials

 * Eddie Weeks (reckless driving causing injury, 1963; guilty)
 * Jessie Brewer and Tom Baldwin (murder of John Prentice, 1968; not guilty)
 * Audrey March Hardy (murder of Peggy Nelson, 1971; not guilty)
 * Diana Taylor (murder of Phil Brewer, 1975; not guilty)
 * Lesley Webber (murder of David Hamilton, 1978; not guilty)
 * Anna Devane (attempted murder of Olivia St. John, 1988; acquitted)
 * Felicia Jones (attempted murder of Ryan Chamberlain, 1993; found guilty but later acquitted)
 * Laura Spencer (murder of Damian Smith, 1996; not guilty)
 * Monica Quartermaine (sexual harassment of Pierce Dorman, 1997; guilty, later exonerated)
 * Tony Jones (kidnapping of Michael Corinthos III, 1998; acquitted)
 * Stefan Cassadine (murder of Katherine Bell, 1998; not guilty)
 * Tom Yergin (blackmail of Emily Quartermaine, 1998; guilty)
 * Luke Spencer (murder of Stefan Cassadine, 2000; acquitted)
 * Jason Morgan and Brenda Barrett (murder of Luis Alcazar, 2003; not guilty)
 * Alexis Davis (murder of Luis Alcazar, 2003; acquitted/self-defense)
 * Nikolas Cassadine (murder of Helena Cassadine, 2004; not guilty)
 * Sonny Corinthos (murder of A.J. Quartermaine, 2005; not guilty)
 * Jason Morgan (murder of Lorenzo Alcazar, 2007; acquitted)
 * Monica Quartermaine (reckless driving causing injury, 2008; sent to rehab)
 * Johnny Zacchara (murder of Logan Hayes, 2008; not guilty)
 * Matt Hunter and Patrick Drake (wrongful death of Brianna Hughes, 2009; charges dropped)
 * Sonny Corinthos (murder of Claudia Zacchara, 2010; charges dropped)

Disasters

 * In September 1977, a hurricane strikes the city, claiming the lives of Martha Taylor and David Hamilton's wife and child.
 * In 1979, further disaster struck the city, when it was hit by an epidemic of Lassa Fever. General Hospital was quarantined for several weeks until a cure was found.
 * In August 1981 the town experienced a blizzard in the midst of summer. The cause of this blizzard was determined to be Mikkos Cassadine's weather machine.
 * In June 1983, General Hospital was taken hostage.
 * In 1987, a DVX hitman holds several GH staff hostage in the Hospital Cafeteria, threatening to unleash the MOX-36 virus. Bobbie Spencer is stabbed with a syringe filled with the virus and ends up paralyzed from the waist down but eventually recovers.
 * In 1988, a bomb explodes in the main exhibition tent of the Port Charles Art Festival.
 * In 1990, a blackout hit the city when Cesar Faison joined together the alien crystals from the planet Lumina.
 * In February 1991, the Quartermaine S.S Tracy sank in the middle of Port Charles Harbor, unleashing toxic chemicals and causing an environmental disaster.
 * In 1991, the town experienced an earthquake, which destroyed many homes and caused a lot of damage.
 * In June 2001, a bus collided head on with a train near the city, interrupting the Nurses Ball, the social event of the year in Port Charles.
 * In February 2004, the Port Charles Hotel burned down. The hotel was completely destroyed, but later rebuilt by Australian billionaire, Jasper Jacks, who renamed it the Metro Court after his now deceased wife, Courtney Matthews.
 * In August 2004, many were trapped at the Quartermaine Mansion while a serial killer was on the loose, killing Sage Alcazar and Trent Parker. This person was Mary Bishop, who also tried to stab Emily Quartermaine.
 * In 2005 Another hurricane struck the city of Port Charles, but fatalities and damage was light compared to the 1977 hurricane.
 * In November 2005, two trains collided in the Glencoe tunnel which is located near the city. Reese Marshall died.
 * In February 2006, a deadly mutant strain of encephalitis had the hospital quarantined for a month and there were several fatalities.With the help of Carly Jacks and Jason Morgan the antidote was found. Sam's brother Danny died.
 * In August 2006, another blackout swept through Port Charles. As a result, Alexis, Sonny, and Kristina were stuck in the Metro Court restaurant.
 * In February 2007, the Metro Court Hotel's lobby was taken hostage and eventually, destroyed by an explosion. This hostage situation lasted for 12 hours. Alan died of a heart attack and Robin and Max were shot.
 * In late 2007 to early 2008 a killer/stalker was in Port Charles as the Text Message Killer. Carly, Sam, Maxie, and more people were attacked by him and he murdered Emily, Georgie, and Michael and Morgan's nanny. The killer was Diego Alcazar.
 * In October 2007, Nikolas Cassadine decided to throw a Black and White Ball for Emily Quartermaine and in honor of the late Dr. Alan Quartermaine. Soon enough, disaster struck in the form of Anthony Zacchara. But it later turned out that there was actually a second intruder Diego Alcazar who was the Text Message Killer (TMK). Diego strangled Emily to death, and nearly strangled Carly Jacks to death as well.
 * In January 2008, a man named Joe Smith strapped a bomb to himself, threatening to blow up the ER unless his wife Angie was given medical attention for her pregnancy. Jason, Elizabeth, Monica, Edward, Epiphany, and Jake were some of the hostages. The bomb turned out to be fake.
 * In March 2008, an abandoned cannery warehouse located on the main docks was blown up by a series of bombs that were planted by the late Diego Alcazar. Carly's unborn baby died.
 * In January 2009, a man released five spheres of boitoxin into the air at the hospital, resulting in several explosions and fires. The hospital burned down. Along the hurt and piosinied people from that night were Claudia, Kate, Sam, and many doctors and nurses inculding Elizabeth, Monica, Matt and many more. Leyla and Trevor were killed.
 * In September 2009, mayhem breaks loose at a carnival benefit for the Michael Corinthos III Pediatric Head Trauma Wing. The Mayor's wife died and Edward, Jake, Kristina, Max, and Dante were all very hurt.
 * From late December 2010 to early January 2011, a bus heading to Cedar Mountain for a ski trip crashes, injuring Olivia Falconeri, Matt Hunter, and Morgan Corinthos, and giving Kristina Davis hypothermia. The bus driver dies on site and Kristina's friend Ali dies at the hospital in-front of Kristina.
 * In June 2011, General Hospital is put on lock down when Lisa Niles takes Patrick Drake, Robin Scorpio-Drake, Steven Webber, and Maxie Jones hostage. Spinelli and Patrick get shot and Lisa is left in a coma.