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290px|left ''The prescription for the residents of Port Charles, New York is the love of power—and the power of love. As their daily lives unfold amidst a backdrop of murder, mob wars, and mansions, the towering face of General Hospital is a constant. It's the town's common arena, and links the Quartermaine, Spencer, Zacchara, and Corinthos families together.''

Main characters

 * T.J. Ashford
 * Shawn Butler
 * Michael Corinthos
 * Sonny Corinthos
 * Alexis Davis
 * Anna Devane
 * Ronnie Dimestico
 * Patrick Drake
 * Dante Falconeri
 * Olivia Falconeri
 * Pres Floyd
 * Max Giambetti
 * Milo Giambetti
 * Kate Howard/Connie Falconeri
 * Matt Hunter
 * Carly Jacks
 * Epiphany Johnson
 * Maxie Jones
 * Ewen Keenan
 * Molly Lansing-Davis
 * Starr Manning
 * John McBain
 * Diane Miller
 * Jason Morgan
 * Sam Morgan
 * Delores Padilla
 * Edward Quartermaine
 * Monica Quartermaine
 * Tracy Quartermaine Zacchara
 * Coleman Ratcliffe
 * Mac Scorpio
 * Felicia Scorpio-Jones
 * Luke Spencer
 * Lulu Spencer-Falconeri
 * Damian Spinelli
 * Elizabeth Webber
 * Heather Webber
 * Steve Webber
 * Maggie Wurth
 * Anthony Zacchara
 * Johnny Zacchara