| Year
|
Title
|
Role
|
Notes
|
| 1982–84
|
General Hospital
|
Blackie Parrish
|
Soap opera
|
| 1984
|
Dreams
|
Gino Minnelli
|
12 episodes
|
| 1985
|
Alice in Wonderland
|
Messenger
|
Movie
|
| 1986–87
|
You Again?
|
Matt Willows
|
Lead role (26 episodes)
|
| 1987–95
|
Full House
|
Jesse Katsopolis
|
Lead role (192 episodes)
|
| 1989
|
The New Mickey Mouse Club
|
Jesse Katsopolis
|
Episode: "Guest Day"
|
| 1990
|
Daughter of the Streets
|
Joey
|
Movie
|
| 1991
|
Captive
|
Robert Knott
|
Movie
|
| 1993
|
The Disappearance of Christina
|
Joe Seldon
|
Movie
|
| Tales from the Crypt
|
Johnny Canaparo
|
Episode: "Till Death Do We Part"
|
| 1994
|
Fatal Vows: The Alexandra O'Hara Story
|
Nick Pagan
|
Movie
|
| 1995; 1997
|
The Larry Sanders Show
|
Himself
|
2 episodes
|
| 1997
|
Tracey Takes On...
|
Rob Trasca
|
Episode: "Movies"
|
| A Match Made in Heaven
|
Tom Rosner
|
Movie
|
| 1998
|
The Marriage Fool
|
Robert Walsh
|
Movie
|
| 1999
|
Sealed with a Kiss
|
Bennett Blake
|
Movie
|
| 2000
|
How to Marry a Billionaire: A Christmas Tale
|
Tom Nathan
|
Movie
|
| 2001
|
Thieves
|
Johnny
|
Lead role (10 episodes); also producer
|
| 2003
|
Clone High
|
Himself (voice)
|
Episode: "Changes: The Big Prom: The Sex Romp: The Season Finale"
|
| Friends
|
Zack
|
Episode: "The One with the Donor"
|
| The Reagans
|
John Sears
|
Movie
|
| 2005
|
The Andy Milonakis Show
|
Himself
|
Episode 3
|
| 2005–06
|
Jake in Progress
|
Jake Phillips
|
Lead role (21 episodes); also producer
|
| 2005–09
|
ER
|
Dr. Tony Gates
|
Lead role (65 episodes)
|
| 2006
|
Wedding Wars
|
Shel Grandy
|
Movie
|
| 2008
|
Comedy Central Roast
|
Himself/Roastmaster
|
Special; episode: "Comedy Central Roast of Bob Saget"
|
| A Raisin in the Sun
|
Carl Lindner
|
Movie
|
| The Two Mr. Kissels
|
Andrew Kissel
|
Movie; also producer
|
| 2010
|
Entourage
|
Himself
|
Episode: "Tequila Sunrise"
|
| 2010–11
|
Glee
|
Dr. Carl Howell
|
4 episodes
|
| 2011
|
Law & Order: Special Victims Unit
|
Ken Turner
|
Season 12 episode: "Bang"
|
| 2011, 2015
|
Two and a Half Men
|
Prospective House Buyer / Himself
|
2 episodes
|
| 2012
|
Secrets of Eden
|
Pastor Drew
|
Movie
|
| 2013
|
The New Normal
|
Brice
|
5 episodes
|
| Necessary Roughness
|
Connor McClane
|
10 episodes (season 3)
|
| Losing It with John Stamos
|
Himself/host
|
Web series (20 episodes); also executive producer
|
| I Am Victor
|
Victor
|
Unsold pilot
|
| 2015
|
Members Only
|
Randy
|
Cancelled before premiere
|
| Galavant
|
Sir Jean Hamm
|
2 episodes
|
| 2015–16
|
Grandfathered
|
Jimmy Martino
|
Lead role (22 episodes); also executive producer
|
| 2016–20
|
Fuller House
|
Jesse Katsopolis
|
Recurring role; also executive producer
|
| 2016
|
Scream Queens
|
Dr. Brock Holt
|
Main role (season 2)
|
| 2017
|
Who Do You Think You Are?
|
Himself
|
1 episode
|
| 2017–20
|
A Capitol Fourth
|
Himself/host
|
Also performed with The Beach Boys
|
| 2018–19
|
You
|
Dr. Nicky
|
Recurring role: season 1; special guest star: season 2
|
| 2019
|
Historical Roasts
|
John Wilkes Booth
|
Episode: "Abraham Lincoln"
|
| The Little Mermaid Live!
|
Chef Louis
|
Special
|
| 2021–22
|
Big Shot
|
Marvyn Korn
|
Lead role
|
| 2021
|
Muppets Haunted Mansion
|
Himself
|
Special
|
| 2022–present
|
Spidey and His Amazing Friends
|
Tony Stark / Iron Man (voice)
|
Recurring role
|
| Mickey Mouse Funhouse
|
Captain Salty Bones (voice)
|
Recurring role
|
| 2023
|
The Prank Panel
|
Himself/host
|
Episode: "Gullible Granny / Pageant Problems"
|
| Harley Quinn
|
Etrigan the Demon
|
"A Very Problematic Valentine's Day Special"
|
